Endocrinology
New York"s Kendra"s Law to provide assisted outpatient treatment for people with severe mental illness is effective in a wide-range of measures, and provides long-lasting benefits the longer someone with a mental illness is in the program, a comprehensive independent evaluation conducted for the state by Duke University Medical School finds.
EndoGastric Solutions (EGS), the recognized leader in the emerging field of Natural Orifice Surgery (NOS), announced that the American Society of General Surgeons (ASGS) has published a position statement endorsing its Transoral Incisionless Fundoplication (TIF) procedure for the treatment of GERD. ASGS is the preeminent society of general surgeons with membership exceeding 2,000.
The Health Law Partners, P.C. released a HealthCare Notification entitled: What All Health Care Providers and Suppliers Need To Know About the Medicare Recovery Audit Contractor (RAC) Program.
The following summarizes selected women"s health-related blog entries.~ "Nine Key Developments in Obama"s Notre Dame Speech," Dan Gilgoff, U.S. News & World Report"s God and Country: When speaking at the University of Notre Dame"s commencement ceremony Sunday, President Obama "devoted a good-sized chunk of the address to confronting the basis for the controversy" surrounding his invitation to speak "head on," Gilgoff writes. He goes on to list nine key points in the speech, including Obama"s decisions to acknowledge the controversy surrounding his appearance at the commencement; highlight his policy proposals of increasing adoption availability and assistance to pregnant women who carry pregnancies to term, which "go way beyond pregnancy prevention;" and voice his support for "drafting a sensible conscience clause," which represents a step away from completely rescinding the Bush administration provider "conscience" rule. Gilgoff writes that Obama also "argued, despite his hopes of achieving common ground around the hottest-button issue, the two sides in the abortion debate really are at loggerheads," adding that his statement was "incongruous with a speech that argued common ground is always possible between ideological combatants." Gilgoff also discusses media coverage of the event and the fact that "Obama never stated his pro-abortion-rights position," which likely will "rile" abortion-rights advocates. In addition, Obama "peppered his speech with shows of respect for those on the other side of the issue," according to Gilgoff. Lastly, Obama addressed the moral issue surrounding abortion, which "represents a break from Democrats who, for a long time, declined to do so," but also spoke on other moral and religious issues beyond abortion -- an important move "because most religious Americans don"t see their faith mostly in terms of stopping abortion" (Gilgoff, U.S. News & World Report"s God and Country, 5/18).~ "Has the Public Become More Opposed to Abortion?" John Sides, The Monkey Cage: Recently released polls from Gallup and the Pew Research Center were based on "hopelessly mushy" questions, and the "findings obscure far more than they reveal," Sides writes. The Gallup data showed that the percentage of people who said they are "pro-life" has risen and is larger than the percentage who calls themselves "pro-choice." The Pew data showed a decline in the percentage of people who think abortion should be legal in "all" or "most" cases, with an increase in the percentage of people who think it should be illegal in all or most cases. However, "a wider array of data do not appear to show notable trends," and the "movement appears to be among Republicans," Sides writes, adding that the two research groups "purport to show shifts in opinion that are not evident in other data." The two groups "employ vague questions that do not easily map onto actual policy debates," he continues, concluding, "Once more precise data are employed, it becomes clear that opinion strongly depends on the circumstances under which the abortion would occur" (Sides, The Monkey Cage, 5/16).~ "Discussion: Obama at Notre Dame," Washington Post"s On Faith: The Washington Post"s On Faith blog posted several entries regarding President Obama"s speech at the University of Notre Dame"s commencement ceremony. Susan Brooks Thistlewaite, a senior fellow at the Center for American Progress, writes that she "appreciated" that Obama"s speech "acknowledged that women are the central decision makers" when it comes to abortion "and that women engage in moral reasoning to make the decision." However, this has "kept religious authorities from making the connection between insights from the history of ethics and the abortion question." Brian McLaren, an evangelical pastor, writes that the speech "was an example of the kind of respectful discourse we need when grappling with issues over which we disagree, while author Susan Jacoby says that the speech and reaction from the audience "will h
Bayer Schering Pharma
A new law requiring the state"s licensed child care centers to educate parents and caregivers about the Consumer Product Safety Commission (CPSC) has taken effect, the Cabinet for Health and Family Services (CHFS) announced.
According to the National Institutes of Health (NIH), about two-thirds of people over the age of 65 have high blood pressure. What"s more, they report that if you haven"t had it by the time you reach age 55, there is a 90 percent chance you will end up with it during your lifetime. It is something that almost all of us will encounter in our lifetime. But the good news is that watching what you eat can go a long way toward helping you avoid high blood pressure and get the problem under control.
The U.S. Food and Drug Administration issued a draft guidance on the use of inks, pigments, flavors, and other physical-chemical identifiers (PCIDs) by manufacturers to make drug products more difficult to duplicate by counterfeiters, and to make it easier to identify the genuine version of the drug.
Results from a study published by the University of Michigan have shown that as many as 15% of women in the study group determined to be negative for the presence of human papillomavirus (HPV) in the cervix, via the most commonly used test for HPV DNA, may actually be infected with the virus at clinically relevant viral loads. PCR-MS detected the presence of high-risk HPV in nearly half (46.7%) of women who tested negative by the Hybrid Capture 2 (HC2) test, which is standard of care in many countries. Approximately 9,000 American women are diagnosed with cervical cancer each year despite regular cervical screening. The study, titled, Development and Evaluation of a PCR and Mass Spectroscopy-based (PCR-MS) Method for Quantitative, Type-specific Detection of Human Papillomavirus, will be published in the September 2009 edition of Journal of Virological Methods. The assay used in this study is exclusively licensed by SEQUENOM (Nasdaq: SQNM).
Cepheid (Nasdaq: CPHD) announced it has received clearance from the U.S. Food & Drug Administration (FDA) to market its Xpert(R) C. difficile test, an on-demand molecular diagnostic test designed for 45-minute detection of the bacterium that causes Clostridium difficile infection (CDI). The Xpert C. difficile test is the first test for CDI to deliver both rapid turnaround and a high degree of accuracy.
The Electronic Health Records Association (EHR Association) has made specific recommendations to the Office of the National Coordinator for Health Information Technology (ONC) on measurable criteria for achieving "meaningful use" of electronic health records (EHRs), as called for in the American Recovery and Reinvestment Act of 2009 (ARRA). The Association specifically calls for 2011 objectives to be based on software and standards that are currently deployed and implemented, with a focus on adoption and use of comprehensive EHRs and recognition of the need for differences between inpatient and ambulatory meaningful use criteria.
The average time patients in Boston wait for an appointment to see a specialist has increased over the last five years to an average of 50 days and can be up to one year, despite the fact that the city has an "abundance" of specialists, according to a recent study, the Boston Globe reports. For the study, Merritt, Hawkins & Associates, a Texas-based consulting and physician recruiting firm, surveyed 1,162 physician offices in 15 metropolitan areas to try to re-create the situation of a new patient seeking a nonurgent appointment in five specialty areas -- cardiology, dermatology, family medicine, obstetrics-gynecology and orthopedic surgery. The average wait time in Boston is more than three weeks longer than any other city included in the study. The study determined that while Boston patients had the longest wait times for appointments to see dermatologists, ob-gyns and family practitioners, Dallas had the longest wait times to see orthopedic surgeons, followed by Boston. Miami, Minneapolis and San Diego all had longer wait times to see cardiologists than Boston.According to the study, while Boston patients have long faced delays, the problem may have been exacerbated by an increase in patients seeking care following the implementation of the 2006 Massachusetts health insurance law. While the study did not pinpoint a cause for longer wait times in Boston, the study"s authors wrote that the city"s experience "may signal what could happen nationally in the event that access to health care is expanded through health care reform."Brian Rossman, research director for Health Care for All, said the reason for long wait times also is because many specialists in Boston work for academic medical centers and do not see patients full time (Kowalczyk, Boston Globe, 5/15).
An article published Online First and in a future edition of The Lancet reports the extraordinary story of Hannah Clark who had a donor heart grafted onto her own after suffering heart failure as a baby. She underwent surgery ten and a half years after the transplant to remove the donor heart. This was possible because her own heart had recovered satisfactorily to work on its own. Today, three and a half years after this second operation, Hannah, now aged 16, has made a complete recovery. The article is the work of leading heart surgeons Professor Sir Magdi Yacoub, Imperial College London, Heart Science Centre, Harefield Hospital, Middlesex, UK, and consultant Victor Tsang, Great Ormond Street Hospital, London, UK and collaborators.
Researchers from the US and Japan studying the new H1N1 pandemic flu virus suggest that it is more virulent than previously thought. They
Memories aren"t made of actin filaments. But their assembly is crucial for long-term potentiation (LTP), an increase in synapse sensitivity that researchers think helps to lay down memories. In the July 13, 2009 issue of the Journal of Cell Biology, Rex et al. reveal that LTP"s actin reorganization occurs in two stages that are controlled by different pathways, a discovery that helps explain why it is easy to encode new memories but hard to hold onto them.
Nanostructured materials have garnered great interest worldwide due to their unique size-dependent properties for chemical, electronic, structural, medical and consumer applications.
An iconic photograph (http://img.timeinc.net/time/80days/images/530228.jpg) of Nobel laureates Drs. Francis Crick and James Watson show the pair discussing with a rigid model of the famous double helix.
The U.S. Department of Justice and 16 states have joined two whistle-blower lawsuits filed in federal District Court in Massachusetts alleging that Wyeth defrauded the government by not offering the same discounts on two medications to Medicaid that it offered to hospitals, the Wall Street Journal reports. The lawsuits were initiated following a grand-jury investigation by the U.S. Attorney"s Office in Massachusetts (Johnson, Wall Street Journal, 5/19). The other states included in the lawsuits are California, Delaware, Florida, Illinois, Indiana, Louisiana, New York, Michigan, Nevada, New Hampshire, Tennessee, Texas, Virginia, Wisconsin and the District of Columbia (Barrett, AP/Austin American-Statesman, 5/18).According to the lawsuits, Wyeth from 2000 to 2006 sold hospitals a bundled package called the Protonix Performance Agreement, which included its acid-reflux drugs Protonix Oral and Protonix IV. The suits allege that Wyeth gave hospitals up to a 94% discount for the oral version under the deal, with the understanding that when patients were released from hospitals they would be switched from the intravenous version of the drug to the oral version. According to the complaint, Wyeth hoped to gain an edge in a competitive market for acid-reflux pills by taking advantage of its standing as the only company offering an IV acid-reflux drug. The Journal reports that Wyeth charged hospitals $20 per vial for the IV version of Protonix and $3 for the oral version.Medicaid rules stipulate that the program is entitled to the lowest price on prescription drugs, and drugmakers are required to pay states rebates if they offer discounts to any other entities. The lawsuits state that Wyeth avoided paying hundreds of millions of dollars to state Medicaid programs because it did not offer the programs the same discounts or provide rebates (Wall Street Journal, 5/19).The lawsuits are seeking financial penalties against Wyeth of up to three times the amount lost by Medicaid. Assistant Attorney General Tony West said, "By offering massive discounts to hospitals, but then hiding that information from the Medicaid program, we believe Wyeth caused Medicaid programs throughout the country to pay much more for these drugs than they should have." Wyeth spokesperson Doug Petkus said that Wyeth "believes that its pricing calculations were correct and intends to defend itself vigorously in these actions" (AP/Austin American-Statesman, 5/18).
President Barack Obama announced his intent to nominate Regina M. Benjamin as Surgeon General, Department of Health and Human Services.
"Lawmakers from both parties are telling the White House they will go on vacation next month and leave behind - and incomplete - President Barack Obama"s health care overhaul," the Associated Press reports. The White House had long pushed lawmakers to complete their proposal by the recess, a target that now appears unlikely.
The Assembly of parliamentarians of Francophone countries have adopted a resolution reaffirming their commitment to the AIDS response. The resolution, which was adopted during their annual assembly which was held from 3 to 6 July 2009 in Paris, gave a strong message that Francophone parliamentarians are continuing to put AIDS high on the agenda and push the response forward in their countries and beyond.
Some seniors in Illinois are delaying buying prescription drugs because of the cost, according to the AARP. United Press International reports: "Twenty-one percent of AARP members surveyed in Illinois report not filling or delaying filling prescriptions due to cost, a survey indicated. Nearly one in five said they had to cut back on food and utilities to afford needed medications, the AARP survey of Illinois residents 50 and over indicated. The survey found 63 percent are concerned about affordability of their prescription drugs. Eighteen percent reported they took less than the prescribed amount to make the medicine last longer. The survey found women and Hispanics say they tend to be harder hit than the general 50-plus population by high drug costs. In the past year, prices for brand-name prescription drugs increased an average of 8.7 percent, while generic drug prices decreased by nearly 11 percent, Merri Dee, president for AARP in Illinois, said. Prices of specialty prescription drugs, used to treat conditions that tend to affect older populations such as cancer and rheumatoid arthritis, increased by 9.3 percent" (7/13).
HHS Secretary Kathleen Sebelius said Sunday the U.S. has agreed to put an addition $1 billion towards ingredients for the production of a vaccine that offers protection against the H1N1 (swine flu) virus, Reuters reports. "There"ll be another $1 billion worth of orders placed to get the bulk ingredients for an H1N1 vaccination. Congress has agreed with the president that this is the number one priority, keeping Americans safe and secure," Sebelius said (7/12).
IRIN examines how a "dramatic plunge" in international donor funding for family planning could undermine other health- and humanitarian-related goals, including fighting poverty and hunger. About 200 million women do not have access to contraception, which could cause a surge in the world"s population leading to a reversal of humanitarian gains, according to some experts.
Near Drought In India Is "Matter Of Concern"
Needle exchange programs (NEPs) "are an inexpensive public health intervention, especially when compared with the social costs of treating individuals with HIV or hepatitis-related chronic liver disease," Maureen Trotter, a pathologist and president of the Taylor-Jones-Haskell County Medical Society, writes in the Abilene Reporter News. She adds that legislation introduced this year in the Texas Legislature "to allow public health departments and organizations to establish disease control programs that provide for the anonymous exchange of used hypodermic needles and syringes for sterile ones, offer education and substance abuse treatment and blood-borne disease testing" failed to come to a floor vote. Trotter further discusses NEPs, citing data on outcomes of NEPs, and writes, "The costs of preventing one case of HIV is estimated between $4,000 and $12,000 via NEPs. The medical cost of treating a person infected with HIV is about $200,000," adding, "These programs, if implemented, could save Texas millions of dollars" (7/12).
Going out like a brilliant flame is one way to get attention. If physicians could watch tumor cells committing a form of programmed suicide called apoptosis, a desired effect of workhorse cancer treatments such as chemotherapy and radiotherapy, they could more quickly pick the most effective treatment. Now scientists at the Stanford University School of Medicine have found a way to do just that, by lighting up cells as they die.
The number of people with Alzheimer"s and dementia - both new cases and total numbers with the disease - continues to rise among the very oldest segments of the population in contradiction of the conventional wisdom, according to research reported today at the Alzheimer"s Association 2009 International Conference on Alzheimer"s Disease (ICAD 2009) in Vienna.
A new study published yesterday looked at "active commuters" who biked or walked to work, and reported they had reduced cardiovascular risk factors. Commenting on the study (1), Ellen Mason, Cardiac Nurse at the British Heart Foundation (BHF) said:
The Kaiser Family Foundation"s Jackie Judd talks with Kaiser Health News" Mary Agnes Carey about upcoming and recent activities on Capitol Hill this week, including the scheduled "s closed-door "walk through" with panel members to discuss options to finance health care overhaul legislation.
It comes as no surprise that some babies are more difficult to soothe than others but frustrated parents may be relieved to know that this is not necessarily an indication of their parenting skills. According to a new report in Psychological Science, a journal of the Association for Psychological Science, children"s temperament may be due in part to a combination of a certain gene and a specific pattern of brain activity.
In the brain, many types of synaptic proteins are spatio-temporally regulated to maintain synaptic activity at a constant level. Here, the Japanese research group led by Professor Masaki Fukata, Drs. Yuko Fukata and Jun Noritake in National Institute for Physiological Sciences, Japan, found that two types of palmitoylating enzymes finely-tune the location and function of a major synaptic protein, PSD-95, in different ways. They also found that this mechanism contributes to keeping synaptic activity stable when synaptic activity dynamically changes. The Japan Science and Technology Agency (JST) supported this study. They report the finding in Journal of Cell Biology published on July 13, 2009.
A new, highly detailed study of the H1N1 flu virus shows that
Results from two large studies using DHA, an omega 3 fatty acid, were
Abraxis BioScience, Inc. (NASDAQ:ABII), a fully integrated biotechnology company, announced that the company has completed patient enrollment of a pivotal, phase III clinical study comparing the company"s chemotherapy agent ABRAXANE® for Injectable Suspension (paclitaxel protein-bound particles for injectable suspension) (albumin bound) with Taxol® (paclitaxel) injection, both in combination with carboplatin, in the first-line treatment of patients with advanced non-small cell lung cancer (NSCLC). The study, which is being conducted at 111 sites globally, includes 1,050 patients and is being led by principal investigator Dr. Mark Socinski at the University of North Carolina Lineberger Comprehensive Cancer Center. It is one of the largest NSCLC clinical studies to complete enrollment.
A new research study published in The Journal of Sexual Medicine and led by noted men"s health researcher Dr. Paul Turek has a powerful conclusion: that men diagnosed with infertility suffer intense negative sexual, personal and social strains that might be considered typical for other medical illnesses, including cancer.
While total knee surgery is a common procedure with a high success rate in the US, getting a second opinion is still recommended. Each surgeon has had a specific training and education, and more experience with certain procedures over others. Some surgeons embrace new technologies and methods while others are more traditional in their practice. Furthermore, you want to feel comfortable with your surgeon. Taking the additional steps to research, interview, and visit more than one doctor can pay off in the long run.
The U.S. Food and Drug Administration said that it will require manufacturers of some immunosuppressant drugs used in kidney (renal) transplantation to update their labeling to reflect an increased risk of infections.
The following statistics were released today by the Department of Health:
Watson Pharmaceuticals, Inc. (NYSE: WPI), a leading specialty pharmaceutical company, announced that it received a Complete Response Letter from the U.S. Food and Drug Administration (FDA) on its New Drug Application (NDA) for TRELSTAR(R) 22.5 mg (triptorelin pamoate for injectable suspension), a 24-week formulation of TRELSTAR(R) for the palliative treatment of advanced prostate cancer. The TRELSTAR(R) NDA was prepared in cooperation with Debiopharm Group, a Swiss-based global biopharmaceutical group of companies.
The American Academy of Dermatology (Academy) recently issued an updated position statement on vitamin D after an updated review of the increasing body of scientific literature on this vitamin and its importance for optimal health.
Lifestyle choices are pieces of the cancer prevention puzzle, but exactly which steps to take remain unclear, even to scientists. Still, more and more individuals are incorporating small changes into their daily routine such as drinking green tea in hopes of keeping cancer risk at bay.
As the Government sets out proposals to reform social care, leading mental health charity Mind welcomes the move to simplify the process and create a fairer system for the many thousands of people with mental health problems who currently pay for social care services.
The Baldwin County Health Department announced that a sentinel chicken from the Lillian area
The American Psychological Association applauded Reps. Patrick Kennedy (D-R.I.) and Ileana Ros-Lehtinen (R-Fla.) for introducing the Positive Aging Act of 2009, a longstanding legislative priority for APA that would improve access to quality mental health care for older adults by integrating mental health services into primary care and community settings where older adults reside and receive services.
"Senators agreed Monday to give high-tech biologic drugs 12 years of market protection before generic versions can compete," according to The Associated Press.
New research showing that "a receptor molecule involved in the recognition of HIV-1 responds to the virus differently in women than in men," might "explain why HIV infection progresses faster to AIDS in women than in men with similar viral loads," the HealthDay/Greenville Daily Reflector reports. The study was conducted by researchers at the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University and will be published in an upcoming issue of the journal Nature Medicine. Study authors also note that during the early stages of infection, women tend to have a stronger immune response to HIV than men, but then progress to AIDS more quickly. The different immune system response "then leads to differences in chronic T-cell activation, a known activator of disease progression, according to the researchers," the article states (7/13). Researcher Marcus Altfeld said the findings raise new questions about how sex hormones affect HIV in the body. "Focusing on immune activation separately from viral replication might give us new therapeutic approaches" to treating HIV, he added (AFP/Google News, 7/13).
The nation"s first online audit of Medicines Use Reviews (MURs) is being launched tomorrow
"Secretary of State Hillary Clinton said Monday she is frustrated over the failure" to name a new head of the USAID, despite it being a priority for the administration, AFP/Google.com reports. "Clinton, addressing USAID staff who asked why there was no administrator and deputy six months into President Barack Obama"s administration, complained about what she called an increasingly burdensome vetting process," the news service writes (7/13).
NICE today welcomed the Office for Life Sciences new Blueprint to support the life sciences industry, which will also improve patient access to innovative new drugs.
International agency Oxfam fears that companies producing affordable generic medicines could be subject to criminal prosecutions and have their medicines seized on orders from big drug companies under plans being drawn up by a closed group of mainly rich countries.
Chronic exposure to tobacco smoke in childhood may contribute to early emphysema later in life, according to new research. Environmental tobacco smoke (ETS) is known to be associated with a variety of serious health problems, but it had not previously been associated with the development of emphysema over the life course. The data was presented on Tuesday, May 19, at the 105th International Conference of the American Thoracic Society in San Diego.
In Scotland, young men and women (ages 35-44) from socially deprived groups are around six times more likely to die from heart disease than the most affluent individuals in the same age range, according to research published on bmj.com today.
A new Mayo Clinic study found that the clinical criteria for mild cognitive impairment is better at predicting who will develop Alzheimer"s disease than a single memory test. This is one more piece of information to aid in the identification and early treatment of individuals most likely to develop Alzheimer"s disease. This study will be presented at the Alzheimer"s Association International Conference on Alzheimer"s Disease on July 14 in Vienna.
The human brain can adapt to changing demands even in adulthood, but MIT neuroscientists have now found evidence of it changing with unsuspected speed. Their findings suggest that the brain has a network of silent connections that underlie its plasticity.
A large study of patients with mild cognitive impairment revealed that results from cognitive tests and brain scans can work as an early warning system for the subsequent development of Alzheimer"s disease.
GenWay Biotech, Inc., a US-based diagnostic company has become CLIA certified and received a California lab license. Their license currently permits the testing of immunological biomarkers. This is a very important step in the direction of commercialization of the novel innovative diagnostic tests currently being developed at GenWay. In upcoming weeks, GenWay will add new cancer biomarker tests to their portfolio as well as several infectious diseases such as sexual transmitted diseases. GenWay is seeking to obtain CAP accreditation by the end of the year.
The National Institutes of Health has awarded a five year $20 million grant to the University of Illinois at Chicago"s Center for Clinical and Translational Science.
NYU and NYU School of Medicine received a $29.4 million, five-year Clinical and Translational Science Award from the National Institutes of Health (NIH) to establish a University-wide Clinical & Translational Science Institute (CTSI) in partnership with the New York City Health and Hospitals Corporation (HHC). The funding is designed to train medical researchers, more rapidly advance science from the lab to the patient to the community and to allow researchers to explore mechanisms of health disparities and develop evidence-based approaches targeted at their reduction. With this grant, NYU, the NYU School of Medicine and HHC will become part of a network of 46 existing Clinical and Translational Science centers based at academic medical centers around the country.
A significantly more accurate* way of calculating the dosimetry of cancer treatments will be introduced by Varian Medical Systems (NYSE: VAR) at the GEC-ESTRO exhibition in Porto, Portgual, on May 14-16. BrachyVision™ Acuros™ enables clinicians to rapidly calculate patient doses for brachytherapy treatments (a form of radiotherapy) with an extremely high level of accuracy.
U.S. House of Representative Democrats unveiled their bill for health care reform - the America"s Affordable Health Care Choice of 2009. In response, National Community Pharmacists Association (NCPA) Executive Vice President and CEO Bruce T. Roberts, RPh, issued the following statement:
Medtronic, Inc. (NYSE:MDT - News) announced completion of enrollment in the TTOP-AF (Tailored Treatment of Permanent Atrial Fibrillation) clinical trial. The study is evaluating the use of the latest radiofrequency (RF) ablation technology, the Medtronic Ablation Frontiers Cardiac Ablation System, for the treatment of continuous atrial fibrillation (AF). A leading advancement from currently available RF ablation tools, the system is comprised of a RF generator (or energy ) and three anatomically shaped mapping and ablation catheters that target three areas of the heart for AF treatment. The system is approved for use in Europe and is under investigational use in the United States.
American Nurses Association (ANA) members joined President Obama at a White House press conference, sending a strong message to Congress that the country no longer can wait to reform health care as rising costs threaten the financial stability of families and their ability to access health care services.
One day after President Obama told lawmakers to speed up their pace, three key Finance Committee senators expressed doubts about meeting the President"s August deadline for passing a reform proposal, Politico reports. Sen. Kent Conrad, D-N.D., said he doesn"t "see how" his colleagues can confirm the new Supreme Court nominee, Sonia Sotomayor, and pass a health bill in the time left before the August recess.
The CFO for Johnson & Johnson"s said President Obama"s deal with hospitals to cut Medicare costs will reduce the sales of medical devices, Bloomberg reports: "Hospitals buy medical devices, including J&J"s artificial hips and stents to prop open clogged arteries, directly from the manufacturer, (Johnson and Johnson CFO Dominic) Caruso said today in an interview with Bloomberg News. The hospitals are reimbursed by government-run health plans for the cost of a procedure regardless of the price of the equipment, pressuring hospitals to cut purchases of the latest technologies, he said. ò€¦ "The deal that the hospital industry struck will obviously have an impact on the medical-device business," Caruso said. "Medicare reimburses the hospital for a basket of costs related to a procedure, of which medical devices are included"" (Randall, 7/14).
Over 80% of rural and remote doctors recently surveyed by the Rural Doctors Association of Australia (RDAA) believe adding a significant rural and remote loading on Medicare items would assist in recruiting and retaining doctors in their communities.
Pfizer Inc announced today results from two Phase 1 safety studies, one of PF-04360365, a humanized anti-amyloid monoclonal antibody (mAb), and another of dimebon (latrepirdine*) in combination with donepezil HCl tablets, in patients with Alzheimer"s disease.1,2 Based on the Phase 1 study results, PF-04360365 has advanced into Phase 2.3 Dimebon (latrepirdine), being co-developed by Pfizer and Medivation Inc., is in Phase 3 development.4 These data were presented this week at the Alzheimer"s Association 2009 International Conference on Alzheimer"s Disease (ICAD) in Vienna, Austria.
The Biotechnology Industry Organization (BIO) testified yesterday before the House Judiciary Subcommittee on Courts and Competition Policy on "Biologics and Biosimilars: Balancing Incentives for Innovation."
Two international research teams have determined the complete genetic sequences of two species of parasitic flatworms that cause schistosomiasis, a debilitating condition also known as snail fever. Schistosoma mansoni and Schistosoma japonicum are the first sequenced genomes of any organism in the large group called Lophotrochozoa, which includes other free-living and parasitic flatworms as well as segmented roundworms, such as the earthworm.
NHS clinical teams will have access to data showing their performance against a set of more than 200 indicators of high quality care in the NHS in one place. It is the next phase in the drive to help NHS professionals improve the quality of care they deliver to patients, and will also support providers and commissioners of NHS services.
Social cognition - the ability to think about the minds and mental states of others - is essential for human beings. In the last decade, a group of regions has been discovered in the human brain that are specifically used for social cognition. A new study in the July/August 2009 issue of the journal Child Development investigates these brain regions for the first time in human children. The study has implications for children with autism.
Young adolescents care a lot about what others think about them. A new study confirms this using brain-mapping techniques that shed new light on this complex period of social development.
More than three-quarters of parents would be willing to permit the use of their children"s newborn screening samples for research purposes if their permission were obtained beforehand, a University of Michigan survey shows.
For parents, summer is the ideal time to ensure college students are prepared academically and financially for campus life. From selecting courses to buying textbooks, there are a number of decisions to be made; however, one important decision - health insurance - is often overlooked. As part of the college preparation process, Aetna (NYSE: AET) encourages parents to also consider their student"s health insurance options before heading off to school.
FUJIFILM Dimatix announced that a research team at McMaster University in Hamilton, Ontario, working with Canada"s SENTINEL Bioactive Paper Network, has used its DMP-2800 Dimatix Materials Printer to develop a new inkjet method for printing bioactive inks (bioinks) on paper strips used to detect harmful substances that can make animals or humans sick or be used as bioterrorism agents.
The California Institute of Quantitative Biosciences (QB3) has joined with the City of San Francisco and FibroGen Inc to launch the QB3 Mission Bay Incubator Network, to spur growth in the bioscience industry.
Senator Sam Aanestad (R-Grass Valley) and Senator Gloria Negrete McLeod (D-Chino) are teaming up in an act of bi-partisan cooperation to serve as joint authors for legislation designed to improve patient safety in California by reforming Medical Peer Review. This is the process where a committee of physicians examines the work of a peer and determines whether the physician under review has met accepted standards of care in rendering medical services.
AARP CEO Barry Rand released this statement following the Senate Health, Education, Labor and Pensions Committee"s passage of the Affordable Health Choices Act:
Advanced Therapeutics & Co. (ADVTX) announced that Fibrinoplate-S™ has shown efficacy in reducing the bleeding in animals exposed to extreme doses of radiation. Survivors of a nuclear event or a dirty bomb explosion will have similar damage from the ionizing radiation of such bombs.
A clinical study published in the journal Phytotherapy Research found that GlucAffect, a nutritional supplement developed by Reliv International, Inc. (Nasdaq: RELV), significantly reduced blood glucose levels and helped control weight in study participants.
Dr. Zsuzsanna Nagy of the University of Birmingham presented data from a clinical study, funded by Cytox Limited, demonstrating that a simple blood-based biomarker discriminated between patients with Alzheimer"s disease (AD) and control subjects. The findings were statistically highly significant, and the test discriminated between the two groups with 80% sensitivity and 80% specificity. The results also showed that 40% of the mild cognitive impairment (MCI) patients tested had the same test results as AD patients. Follow up study of MCI patients enrolled in an earlier study found that the test allowed early identification of those MCI patients who later developed dementia. The results were presented at the 2009 Alzheimer"s Association International Conference on Alzheimer"s Disease (ICAD 2009), held in Vienna, Austria.
Have you seen the commercial for in-office procedures that will make your face wrinkle-free or sculpt your stomach, with no downtime and no scars? Lifestyle Lift, Lunchtime Lift, Thread-Tox, and Smart-Lipo, are just a few of the brand-name surgical procedures being marketed to the public as a cosmetic quick fix with a clever name.
The government"s Green Paper "Shaping the Future of Care Together" has been welcomed by the MS Society as the radical step necessary to address the crisis in social care.
Senate Finance Committee ranking member Chuck Grassley (R-Iowa) and committee Chair Max Baucus (D-Mont.) have been privately negotiating over how their panel"s version of health reform legislation will address abortion coverage, Newsweek reports. According to Newsweek, Grassley has been pushing to include measures that would prohibit what he considers "taxpayer-subsidized abortion."Earlier this month, NARAL Pro-Choice America, Raising Women"s Voices and other women"s health advocates intensified efforts to ensure that abortion access was treated like access to all other services in health care reform, according to Newsweek. The article points out, "Though usually publicly debated in the language of personal liberty and morality, abortion is a medical procedure performed by a doctor. It"s currently covered by most private insurance plans and existing government programs, at least under some circumstances. This expanded federal oversight and use of federal dollars raises several thorny issues." Grassley is urging that federally regulated and subsidized plans be prohibited from covering the procedure. Lawmakers also could weigh whether religious organizations -- such as Catholic hospitals or health plans -- could opt out of the coverage.Jill Kozeny, Grassley"s spokesperson, said the senator "is opposed to mandating abortion coverage in health care legislation." According to his office, "At one point during the recent negotiations, there was a (compromise) solution that didn"t work out." Grassley -- who is known as a staunch opponent of abortion rights -- said in March, "I take a view that there is almost anything compromisable in public affairs. Abortion is about the only issue I know of that"s not compromisable."Baucus" office declined to comment on the legislation, citing "longstanding Finance Committee policy not to discuss the specifics of ongoing negotiations." Erin Shields, Baucus" press secretary, noted that the lawmaker has a 100% approval rating from NARAL. She added, "He has always fought for a woman"s right to choose and will continue to do so."According to Newsweek, the House"s and the Senate Health, Education, Labor and Pensions Committee"s proposals do not specify covered benefits, instead leaving the decision to an independent commission or the HHS secretary. A recent National Women"s Law Center poll found that 62% of participants would oppose a provision excluding abortion and family planning coverage (Feder, Newsweek, 7/14).
In President Obama"s push for health reform, "new fault lines are opening up everywhere you look. Liberals are worried that Obama is going squishy on including a strong, government-run "public option" among the health-care choices available to Americans. Conservatives are warning that the legislation won"t do enough to control health costs. Rural lawmakers are complaining that proposed Medicare cuts will fall too hard on their states," TIME reports. "And those are just the arguments going on among the Democrats. It"s all a sign that the season for hard decisions has arrived. Obama continues to project an air of confidence about the most audacious undertaking of his presidency" (Tumulty, 7/16).
"This is Year 20 for America"s Best Hospitals, a tool for patients who need medical sophistication that most facilities are unable to provide," reports U.S. News and World Report. The magazine ranked hospitals based on how well they did in "complex and demanding situations" such as "replacing an 85-year-old"s heart valve, diagnosing and treating a spinal tumor, and dealing with inflammatory bowel disease." Out of a total 4,861 hospitals analyzed, "Only 174 hospitals scored high enough to be ranked in even one of the 16 specialties. And of these, just 21 qualified for [the] Honor Roll by ranking at or near the top in at least six specialties." The ranking list includes the 50 highest scoring hospitals (Comarow, 7/15).
Scientists at the Wellcome Trust Sanger Institute have discovered a set of brain proteins responsible for some of the most common and devastating brain diseases. The proteins underlie epilepsy, depression, schizophrenia, bipolar disease, mental retardation and neurodegenerative diseases including Alzheimer"s and Huntington"s diseases.
The board of directors of Medtronic, Inc. (NYSE: MDT), announced that the company"s annual meeting of shareholders will be held at 10:30 a.m., Central Daylight Time, on Thursday, August 27, 2009 at Medtronic World Headquarters, located at 710 Medtronic Parkway, Minneapolis, Minnesota. Shareholders of record at the close of business on June 29, 2009, will be eligible to vote at the meeting.
US researchers have discovered the molecular mechanisms by which the human body metabolizes selenium, a trace element that plays an essential
Data presented at the annual meeting of the International Society on Thrombosis and Haemostasis (ISTH) in Boston show that ATryn® (Antithrombin [Recombinant]) safely prevents peri-operative and peri-partum acute deep vein thrombosis (DVT) or other venous thromboembolic events in patients with hereditary antithrombin deficiency (HD AT). ATryn is not indicated for treatment of thromboembolic events in HD AT patients. Additionally, data validate dosing algorithms that, along with AT activity monitoring, allow physicians to normalize antithrombin levels during the high-risk situations of surgery and childbirth.
Cambridge University researchers have discovered that whether someone is a "people-person" may depend on the structure of their brain: the greater the concentration of brain tissue in certain parts of the brain, the more likely they are to be a warm, sentimental person.
The NPHS influenza surveillance scheme, which records reports of diagnoses of flufrom more than 300 GP practices across Wales, shows low but increasing levels of influenza activity across Wales. Further detail can be found on the NPHS website.
Given equivalent results with regards to survival, the impact of anastomotic methods on QOL becomes even more important. There is still no consensus on how to choose a reconstruction method for proximal gastrectomy in patients with upper third gastric cancer.
Clarithromycin is currently one of the antibiotics used for eradication of Helicobacter pylori. However, reports of H. pylori resistance to this antibiotic are increasing worldwide. Clarithromycin resistance has been attributed to the presence of mutations in the 23S rRNA gene, a component of the ribosome that is the protein manufacturing machinery of all living cells. There is little information on the prevalence and characteristics of clarithromycin resistance in H. pylori strains isolated from Malaysian patients.
American Medical Systems, Inc. (AMS) (NASDAQ: AMMD) a trusted provider of medical solutions for restoring men"s and women"s pelvic health, announced that its AMS 700® with INHIBIZONE® has been approved by the U.S. Food and Drug Administration (FDA) as the only inflatable penile prosthesis with clinical evidence showing a significant reduction in the rate of revision surgery due to infection.
A UQ institute has joined forces with a leading American university to work on research to change the way we live.
Recent disruptions in the supply of anti-retroviral (ARV) drugs and other essential medical items in at least six African countries are putting HIV patients" lives at risk, said the international medical humanitarian organization Doctors Without Borders/Mç©decins Sans Frontiç¨res (MSF) today, in advance of the International AIDS Society Conference in Cape Town, South Africa.
AlphaVax, Inc. announced today that it has completed process development and preclinical immunogenicity studies of its H1N1 (swine) influenza vaccine and will manufacture clinical trial material by the end of the month. This vaccine has shown good production yields as well as excellent immunogenicity, even after just a single inoculation.
Bionovo, Inc. (Nasdaq: BNVI) announced that a study of the gene regulation in multiple cell lines by several of their estrogen receptor beta (ERb) candidates will be published in Public Library of Science One.
Researchers from Weill Cornell Medical College have published results showing that a new contraceptive device may also effectively block the transmission of the HIV virus. Findings show that the device prevents infection by the HIV virus in laboratory testing. The promising results are published in the most recent issue of the journal AIDS.
Pain symptoms that cannot be attributed, or at least not fully attributed, to an organic origin are more frequently and more severely experienced by patients with depression than by those without. "It is the case that women are much more frequently affected by depression and also by so-called somatoform pain disorder than men," explains Dirk Frieser, psychologist at the Institute of Psychology at Johannes Gutenberg University Mainz. For the purposes of his doctoral dissertation, Frieser and fellow psychologist Stephanie Kç¶rber questioned 308 patients attending two practices of general practitioners in Mainz. Patients were asked about their state of health and their pain symptoms, but also about their anxieties with regard to illness, how they react when ill, what social support they receive, and what psychological stress they experience, together with many other aspects. Subsequently, the pain symptoms reported by the patients were evaluated by their doctors.
The House Ways and Means Committee passed the House version of a health care reform bill early Friday morning, approving as much as a 5.4 percent surtax on the wealthy to pay for it and readying for a fight, Bloomberg reports.
Hospitals across Canada are seeking ways to free up beds. University of Alberta researcher Donna Wilson has a suggestion: people should be encouraged to die at home rather than in hospital.
One Maryland county"s tiny new health care programs for the uninsured could be a model for providing care nationwide, National Public Radio says in an ongoing series. The program is cheap, effective and heavy on preventive care, Howard County"s health commissioner, Dr. Peter Beilenson says. The program, called Healthy Howard, provides care for families of four earning up to $66,000 a year, and patients are required to pay $50 to $85 a month. But some of the enrollees are running into trouble.
California cuts back on health insurance for children, while New Hampshire expands state insurance to young adults. Meanwhile, a regional health commission in Missouri hopes to help the uninsured, and an Iowa report concludes that minorities face discrimination in the health care system.
New vaccines against rotavirus, "the leading cause of severe diarrhea in infants," can prevent or lessen the severity of an epidemic, protect unvaccinated children and increase the age of first infection, lessening the severity of the disease, according to a study published in the journal Science, Bloomberg reports (Olmos, 7/16).
The U.N. Office for the Coordination of Humanitarian Affairs (OCHA) issued an alert on Thursday "seeking donor help" to address the health situation in southern and central Somalia, "which has continued to deteriorate due to latest fighting in [the capital of] Mogadishu," Xinhua reports. In the alert, OCHA said civil strife has had a "debilitating effect" on the social services infrastructure - particularly health services - in the country, Xinhua writes. "With the country already facing one of the highest infant and maternal mortality rates in the world, the humanitarian health community is finding itself constrained by the health funding deficit, leaving a number of critical life-saving health projects uninitiated and ongoing ones under threat of cessation," OCHA said.
NHS South West Essex has launched an ambitious mobile MMR immunisation programme to improve vaccination rates among 20,000 at risk children.
By manipulating individual atoms in DNA and forming unique molecules, a Georgia State University researcher hopes to open new avenues in research towards better understanding the mechanisms of DNA replication and transcription, and perhaps leading to new treatments for diseases.
Texas Medical Association (TMA) statement from TMA president William H. Fleming III, MD, regarding H.R. 3200, "America"s Affordable Health Care Choices Act of 2009," Congressional legislation to reform America"s health care system.
The American Hospital Association announces the 2009-2010 class of Patient Safety Leadership Fellows. Thirteen individuals have been selected to participate in this year"s fellowship class.
The American Nurses Association (ANA) reached out to lawmakers Friday, with a letter in support of H.R. 3200 "America"s Affordable Health Choices Act of 2009." After a contingent from ANA took part in a Rose Garden press conference with President Obama July 15th, ANA set out to engage lawmakers, nurses, and other health professionals across the country to voice their commitment to real healthcare reform.
THEY work in all corners of the hospital, carrying out a diverse range of jobs but these dedicated staff have one thing in common - they"re all Shining Stars.
A study which found up to one third of GPs are planning to retire early highlights the need for governments to boost support for general practice, AMA Federal President, Dr Andrew Pesce, said today.
EFPIA, the voice of the pharmaceutical industry in Europe, of which the Irish Pharmaceutical Healthcare Association (IPHA) is a member, has announced an important step in the industry"s efforts to protect Europe"s citizens against counterfeit medicines. EFPIA has agreed to run a pilot of its coding and identification solution (1) in Sweden later this year in partnership with Swedish retail pharmacy chain Apoteket AB and local wholesalers Tamro and KD.
A new, intensive, one-year master"s degree program designed to prepare graduates for informatics leadership positions in clinical, public health and scientific settings will be offered beginning in September by the Johns Hopkins University School of Medicine. The Maryland Higher Education Commission (MHEC) approved the new program in June.
An initiative to boost cancer prevention, treatment and care throughout Europe by improving communications within the cancer community kicks off today (Monday 20 July) with the launch of a new website: http://www.eurocancercoms.eu. The project will involve all those with an interest in cancer, from researchers and doctors to patients.
Mathematical modelling can help inform public health policy in outbreaks such as the H1N1 pandemic, write members of the Pandemic Influenza Outbreak Research Modelling Team in Canada in a CMAJ (Canadian Medical Association Journal) article http://www.cmaj.ca/press/cmaj090885.pdf. These models are useful tools for simulating plausible scenarios, developing control strategies and identifying important areas for immediate research.
Why do we feel tears well up when we see a loved one cry? Why do we wince when we see other people hurt themselves? Here we review evidence that when people observe the actions and tactile sensations of others they activate brain regions that are also active when they perform similar movements and feel similar sensations themselves.
Commenting on today"s speech by Conservative Party Leader Rt
This afternoon, AARP CEO A. Barry Rand delivered the following remarks at the White House Middle Class Task Force Town Hall in Alexandria, Va., during a discussion with Vice President Biden, Health and Human Services Secretary Kathleen Sebelius, and White House Office of Health Reform Director Nancy-Ann DeParle, on how health care reform will lower costs, cut waste, and improve quality for seniors from across the country.
Data from two presentations highlighting the use of Perforomist® (formoterol fumarate) Inhalation Solution in moderate to severe chronic obstructive pulmonary disease (COPD) patients were featured at the International Conference of the American Thoracic Society in San Diego. In one analysis, use of Perforomist Inhalation Solution, when added to maintenance tiotropium, resulted in improved pulmonary function, dyspnea (shortness of breath) and rescue medication use versus treatment with tiotropium alone. In a second study, patient satisfaction increased in those treated with Perforomist Inhalation Solution twice daily compared with ipratropium/albuterol metered-dose inhaler (MDI) four times daily.
Data from a historic HIV study demonstrate that it is possible to recruit large numbers of women, African Americans and Latinos into U.S.-based HIV-1 treatment studies. The study, known as GRACE, is the largest study to date in treatment-experienced adult women with HIV-1 to examine gender and race differences in response to an HIV-1 therapy -- PREZISTA(R) (darunavir) coadministered with ritonavir as part of combination therapy. GRACE findings were presented at the 5th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention (IAS 2009) in Cape Town, South Africa.
From the start of the HIV epidemic, it appeared that some of the people who were infected with the virus were able to ward off the fatal effects of the disease longer than others. Recent studies have begun to unravel the cause of this phenomenon, and new research suggests that African Americans with the disease have a unique survival advantage if they have both a low white blood cell count (known as leukopenia) and a genetic variation that is found mainly in persons of African ancestry. This study was prepublished online on July 20, 2009, in Blood, the official journal of the American Society of Hematology.
Scientists have worked for 20 years to perfect gene therapy for the treatment of cystic fibrosis, which causes the body to produce dehydrated, thicker-than-normal mucus that clogs the lungs and leads to life threatening infections.
Transoral (through-the-mouth) laser surgery to remove cancer at the base of the tongue is as effective as more invasive open surgery and may improve quality of life according to a new study by Rush University Medical Center. The study is published in the July issue of the scientific journal Otolaryngology Head and Neck Surgery.
The development, which has taken five years to complete, is part of a ÷£500m PFI scheme, commissioned by Central Manchester University Hospitals NHS Foundation Trust (CMFT), and delivered in partnership with Catalyst Healthcare. The new Royal Manchester Children"s Hospital - a "super-hospital" for children - will be accompanied by The Manchester Royal Infirmary, Saint Mary"s Hospital and Manchester Royal Eye Hospital.
In an appearance on "Fox News Sunday," White House Office of Management and Budget Director Peter Orszag said that he is "not prepared to say explicitly" whether health care reform legislation would prohibit the use of federal tax revenue to fund abortion coverage, the New York Times reports. Orszag"s statement came in reply to a question asking whether he was prepared to say that "no taxpayer money will go to pay for abortions." Orszag said, "It"s obviously a controversial issue, and it"s one of the questions that is playing out in the debate" (Pear/Liptak, New York Times, 7/20).Sen. Judd Gregg (R-N.H.), who also appeared on "Fox News Sunday," said, "No matter what your views are on abortion, you shouldn"t ask people to use their tax dollars if they think that abortion is taking a life." Gregg added, "I would hate to see the health care debate go down over that issue. We do really need health care reform, and it has to be substantive. ... So hopefully we won"t get ourselves wrapped around the wheel of abortion in this debate" (FoxNews.com, 7/19). According to the Times, there is an ongoing behind-the-scenes debate over handling abortion coverage in health overhaul legislation. The debate affects both the public insurance plan the legislation would create and private insurers, who would receive tens of billions of dollars in federal subsidies to expand coverage for low- and moderate-income U.S. residents. A provision in the House health reform bill (HR 3200) calls for a federal advisory committee to advise the HHS secretary on an "essential benefits package" that most insurers would be required to provide. Abortion-rights opponents want abortion coverage excluded from the package, while abortion-rights advocates say the decision should be left to medical professionals. House committees working on health reform legislation have rejected Republican amendments that would have restricted abortion coverage. The Hyde Amendment, first enacted in 1976, prohibits the use of federal Medicaid money for abortion services. However, abortion-rights opponents argue that federally subsidized coverage of the uninsured would not be subject to the existing restrictions. The National Right to Life Committee issued an analysis of the House bill, stating, "There is no doubt that coverage of abortion will be mandated, unless Congress explicitly excludes abortion from the scope of federal authority to define "essential benefits."" According to the group, even if the HHS secretary did not require abortion coverage, "federal courts would interpret the broadly worded mandatory categories of coverage to include abortion" (New York Times, 7/20).
Behavioural ecologists working in Bolivia have found that wild spider monkeys control their diets in a similar way to humans, contrary to what has been thought up to now. Rather than trying to maximize their daily energy intake, the monkeys tightly regulate their daily protein intake, so that it stays at the same level regardless of seasonal variation in the availability of different foods.
Although several studies have shown that circumcision, removal of the foreskin which contains cells that are particularly susceptible to HIV, appears to reduce a man"s risk of contracting HIV from his female sex partner, it does not reduce the female sex partners" risk of contracting the virus, according to a study in the Lancet, Reuters reports. Maria Wawer of Johns Hopkins University and colleagues in Uganda followed 922 HIV-positive, uncircumcised men ages 15 to 49. Some of the men immediately underwent a circumcision, and some had the procedure two years later. The researchers also followed 163 female partners of the men.The researchers decided to end the study early when they found that male circumcision did not convey the expected benefits to women. The study also found that men"s partners were no less likely to contract other sexually transmitted infections, except for trichomonas.However, based on observational studies, researchers say that circumcision is so effective in protecting men that it will still likely benefit women indirectly by reducing circulation of the virus in general (Fox, Reuters, 7/16).