Diagnostics
Health experts and politicians filled Sunday talk shows as Obama administration officials push for reform.
The British Medical Association in Northern Ireland (BMA(NI)) and members of its Patient Liaison Group welcomed the Northern Ireland Assembly debate on "Health Provision for Older People", which had previously been postponed.
"Small business is suddenly playing a big role in negotiations over health care," NPR reports. "Supporters and opponents of various plans to overhaul the system are all trying to paint themselves as champions of mom and pop entrepreneurs." The National Federation of Independent Business is "not happy with the health care bill taking shape in the House this week - especially its requirement for all but the smallest employers to provide health insurance or pay a penalty." Meanwhile, "the Democratic National Committee quickly lined up its own panel of small business owners to defend the House plan."
The insurance industry so far has "stayed at the bargaining table and held its fire in the ad wars," but "now, the industry is speaking up, not with an attack but with a seven-figure, national cable TV ad buy starting Monday in favor of affordable bipartisan health reform that can cover everyone," Politico reports. "But make no mistake: The ads are sending a strong don"t-tread-on-us message, not so much a shot across the bow of reform as a reminder of the industry"s ability to weigh in at any time, with messages pro or con." The 30-second ads from America"s Health Insurance Plans (AHIP) "pushes for bipartisan reform that includes affordable, universal coverage that doesn"t deny insurance to those with pre-existing health conditions," but doesn"t attack the idea of a government-run insurance plan - a proposal the industry vehemently opposes." The ad "will be supported by a complementary print campaign that is also set to launch this week."
More than 1,000 global experts will gather in Dubai from 8-9 November 2009 to review the latest developments and trends in anti-aging medicine at the second Dubai Congress on Anti-Aging & Aesthetic Medicine (DCAAAM).
Building on its widely distributed multiplex PCR technology platform, Seegene is now providing healthcare systems worldwide with a powerful diagnostic test for effective identification of the new influenza A virus (swine H1N1).
Stem Cell Therapeutics Corp. (TSX VENTURE:SSS)("SCT" or "the Company") has received a No Objection Letter ("NOL") from Health Canada for the modified REGENESIS protocol using NTx®-265 for a Phase IIb clinical trial treating acute ischemic stroke.
A study to be published in the August 2009 edition of Applied Cognitive Psychology sheds new light on how Cogmed Working Memory Training and stimulant medication address working memory impairments in children with ADHD. Working memory, acknowledged as one of the core deficits in ADHD, represents the brain"s ability to hold and process critical information related to the present moment. This study represents the latest findings from a team of independent UK researchers whose ongoing work examines the impact of Cogmed"s software-based training program on individuals with disorders of memory and attention.
U.S. Lawmakers Should Not Slow AIDS Funding
More people would benefit and it would be more cost effective if HIV treatment with antivirals started earlier in countries like South Africa where medical res are limited, said researchers.
The Inland Empire HIV Planning Council, an agency that makes HIV/AIDS policy in Riverside and San Bernardino counties in California, has begun a three-day summit, where they will determine how funds - primarily from HHS - will be spent, the Riverside Press-Enterprise reports. The council, which oversees spending of more than $7 million for HIV/AIDS care and treatment in the counties, said proposed cuts to HIV/AIDS programs and Medi-Cal at the state level "could affect funding and treatment priorities set by the agency," the article states. Joe Acosta, co-chair of the council said they are looking for ways to make up for the expected shortfalls. The council distributes money to about a half dozen agencies in San Bernardino and Riverside counties that provide services to more than 6,800 HIV/AIDS patients, Acosta said" (Hines, 7/18).
Visitors at next week"s Royal Bath and West Show will have the opportunity to find out what jobs and training schemes are on offer at Yeovil District Hospital.
Secondhand smoke (SHS) is not only a nuisance, but a potential health concern for many college students, and administrators should be taking steps to reduce students" exposure, according to a new study by researchers at Wake Forest University School of Medicine.
The NPHS influenza surveillance scheme, which records reports of diagnoses of flu from more than 300 GP practices across Wales, shows low but increasing levels of influenza activity across Wales. Further detail can be found on the NPHS website: click here.
Mild facial nerve paralysis caused by the use of forceps during birth generally resolves on its own and does not require treatment, according to a report in the July issue of Archives of Otolaryngology-Head & Neck Surgery, one of the JAMA/Archives journals.
Every time a neuron sends a signal - to move a muscle or form a memory, for example - tiny membrane-bound compartments, called vesicles, dump neurotransmitters into the synapse between the cells. Researchers report that this process, which is fundamental to the workings of the nervous system, relies on a simple mechanical reality: Tension in the axon of the presynaptic neuron is required.
Scientists have identified a master regulator gene for early embryonic development of the pancreas and other organs, putting researchers closer to coaxing stem cells into pancreatic cells as a possible cure for type1 diabetes.
Nycomed announced the submission of a New Drug Application (NDA) to the US Food and Drug Administration (FDA) for Daxas® as a once-daily oral treatment for patients with symptomatic COPD. The NDA submission is based on encouraging results from four Phase III trials of Daxas® (roflumilast) in the treatment of symptomatic COPD. Two pivotal 12-month studies showed positive effects on exacerbation rates and pulmonary function (FEV1). Two supporting six-month studies also confirmed the efficacy of Daxas when used with standard bronchodilator treatments. Full data from all four studies are to be published during 2009.
Following the disbandment of the STEP trial to test the efficacy of the Merck HIV-1 vaccine candidate in 2007, the leading explanation for why the vaccine was ineffective - and may have even increased susceptibility to acquiring the virus - centered on the hypothesis that high levels of baseline Ad5-specific neutralizing antibodies may have increased HIV-1 acquisition among the study subjects who received the vaccine by increasing Ad5-specific CD4+ T-cells that were susceptible to HIV-1 infection.
"Single-Shot" Vaccines May Protect Against H5N1 Influenza Virus
Stagnation in HIV/AIDS funding and the high cost of new medicines are putting the lives of thousands of poor patients at risk, the international medical humanitarian organization Doctors Without Borders/Mç©decins Sans Frontiç¨res (MSF) warned today at the 2009 International AIDS Society conference in South Africa . Patients needing new drug regimens will return to AIDS "death row." While the lack of access to antiretroviral treatment for seven million people remains unaddressed, inadequate financing now further threatens treatment scale-up.
A new Bachelor of Occupational Health and Safety Science that offers career opportunities in a diverse range of workplaces, from mines to movie sets, will be on show at UQ"s St Lucia Open Day (August 2).
University of Queensland researchers will use a $2.5 million grant to help people who have suffered an acquired brain injury communicate with the world.
The World Health Organization (WHO) said earlier today, Tuesday, that countries should consider closing schools as a way to slow the spread of
ImClone Systems, a wholly-owned subsidiary of Eli Lilly and Company (NYSE: LLY), and Bristol-Myers Squibb Company (NYSE: BMY) today announced that the U.S. Food and Drug Administration (FDA) has approved revisions to the U.S. prescribing information for ERBITUX® (cetuximab) concerning the treatment of patients with epidermal growth factor receptor (EGFR)-expressing metastatic colorectal cancer (mCRC). The labeling revisions include a modification to the indication, which now includes a statement that retrospective subset analyses of metastatic or advanced colorectal cancer trials have not shown a treatment benefit for ERBITUX in patients whose tumors had K-ras mutations in codon 12 or 13 and that the use of ERBITUX is not recommended for the treatment of colorectal cancer with these mutations. Revisions concerning the use of ERBITUX in colorectal cancer tumors with K-ras mutations were also made to the clinical studies and clinical pharmacology sections of the product"s prescribing information.
LDR, a total spine solution company, announced that it has begun to market its ROI-C™ cervical cage following 510(k) clearance from the United States Food and Drug Administration. The ROI-C cage, when used with the company"s integrated VerteBRIDGE™ plating technology, offers a zero profile, stand-alone construct for fusion in the cervical spine. ROI-C addresses the growing interest within the market for stand-alone cervical fusion technology that reduces the need for thick cervical plates that may contribute to dysphagia, or difficulty swallowing.
There is no evidence that giving infants a combination vaccine for diphtheria (D), tetanus (T), pertussis (P), hepatitis B (HBV), and Haemophilus influenza type B (Hib) protects them as effectively as separate vaccines, according to the results of a new Cochrane review.
University of Utah School of Medicine researchers and their colleagues at University of Texas (UT) Southwestern Medical Center have found strong evidence that abnormal calcium signaling in neurons may play an important role in the development of spinocerebellar ataxia type 2 (SCA2), a disorder causing progressive loss of coordination, speech difficulty, and abnormal eye movements. Their findings are published in the July 27, 2009 issue of Journal of Neuroscience.
Improving communications skills and the use of a simple blood test could help cut the growing
The UK needs a national plan for dementia research or the country will pay the price, the UK"s top scientists are warning today.
In a speech at the National Press Club in Washington, D.C., Gail McGovern, President and CEO of the American Red Cross, described the challenges of running a nonprofit in the recession but also pointed to success in cutting the organization"s deficit by 75 percent and surpassing its goal of raising 100 million in nine months.
The Kansas chapter of the National Organization for Women has formed its own political action committee to replace ProKanDo, a PAC founded in 2002 by abortion provider George Tiller that was closed after his murder in May, the AP/Hays Daily News reports. ProKanDo spent more than $1 million over the last four years to advocate for abortion rights, assist candidates who support abortion rights and oppose antiabortion-rights candidates. The organization had more than 6,400 contributors but received between one-third and one-half of its annual funding from Tiller, according to former Director Julie Burkhart.NOW has scheduled a conference in Wichita on July 25 to discuss legislative strategy and Kansas elections. Marla Patrick, coordinator of NOW"s Kansas chapter,÷ said that although the new PAC will not have the same financial support from Tiller that ProKanDo received, his death has invigorated grassroots support. She added, "I think that can be every bit as effective, if not more so, especially in light of all the recent events" (Hegeman, AP/Hays Daily News, 7/18).
Four newspapers recently published editorials responding to last week"s confirmation hearings for Supreme Court nominee Sonia Sotomayor. Summaries appear below.~ Boston Globe: Sotomayor "far surpassed" the "meager standard" of "just [having] to avoid saying anything damaging," according to a Globe editorial. During the hearings, she "made it clear she believes that Supreme Court justices base their decisions on the Constitution, the law and the relevant precedents," and her "judicial record offers no reason to think otherwise," the editorial states. It continues that "the hearings did nothing to undermine -- and much to underscore -- the notion that Sotomayor has the right temperament, intellect and credentials for the Supreme Court. She should be confirmed" (Boston Globe, 7/20).~ New York Times: The Senate "has learned more than enough about [Sotomayor"s] qualifications to give her a seat on the court," according to a Times editorial. However, "[i]t would also be good if senators -- and the nation -- had a deeper sense of her views on some of the most pressing legal questions of our times," the editorial continues. It adds, "We were disappointed that at her confirmation hearings last week, she continued what is becoming an unbreakable habit of nominees dodging controversy." For example, "[w]e would have liked to hear her boldly defend the idea of the Constitution as a living document, one that changes with the times," and "we would have preferred if she had used the hearings to explain to the public that the much-mentioned distinction between judges making and applying the law has little meaning," the editorial states. Sotomayor "avoided saying much of substance about abortion rights, the scope of presidential power, and other hot-button issues," although this is "not entirely her fault," as the "Senate has shown repeatedly that it will tolerate this sort of evasion." However, "the public has a right to know where judicial nominees stand on important legal issues that will have a direct impact on their lives," the editorial states. It concludes, "We hope the Senate confirms her without delay so we can see more clearly what her contribution will be" (New York Times, 7/21).~ Washington Post: During her confirmation hearings, Sotomayor "proved herself well-qualified and worthy of confirmation," according to a Post editorial. The editorial continues, "She spoke convincingly about her belief in and record of consistently respecting legislative prerogatives -- an approach that signals a modest style of judging." Although the hearings focused on Sotomayor defending her previous speeches and comments, her "attempts to explain away and distance herself" from the statement that a wise Latina might make a better decision than a white man "were unconvincing and at times uncomfortably close to disingenuous, especially when she argued that her reason for raising questions about gender or race was to warn against injecting personal biases into the judicial process." The editorial adds, "Her repeated and lengthy speeches on the matter do not support that interpretation." According to the Post, "It"s too bad that she felt she had to disavow her true intent, because, though a wise Latina won"t necessarily judge better than a white man would, diversity on the bench is indeed important" (Washington Post, 7/19).~ Washington Times: During the hearings, Republican senators "failed to ask questions of great relevance to public understanding of the judge"s record and integrity," a Times editorial states. The editorial continues, "They owe it to all Americans to get tough enough to force an examination of whether the judge may have perjured herself during her testimony." According to the editorial, "The questions for which Judge Sotomayor"s answers are almost impossible to believe involved legal briefs on abortion cases that were filed by the Puerto Rican Legal Defense and Education Fund during the 12 years Judge Sotomayor sat on its board." Republican senators also "failed to ask sharp f
Health reform legislation moving through the U.S. House of Representatives would reverse the continued and growing loss of health coverage by American families and would give millions of Americans the security of stable, quality, affordable coverage, according to a report released today by the consumer health organization Families USA.
Chemotherapy is the use of chemicals (medication) to treat disease - more specifically, it usually refers to the destruction of cancer cells. However, chemotherapy also includes the use of antibiotics or other medications to treat any disease. This article focuses on chemotherapy for cancer treatment. Cytotoxic medication prevents cancer cells from dividing and growing. When health care professionals talk about chemotherapy today, they generally tend to refer more to cytotoxic medication than others.
Genetic testing services have recently begun to be advertised directly to the patient, and the results of the consumers" response can affect public health, as well as the future adoption of pharmacogenetic/genomic testing, according to a position paper from the American College of Clinical Pharmacology (ACCP) to be published in the August 2009 issue of the Journal of Clinical Pharmacology. The journal is published on behalf of the ACCP by SAGE.
Healthy, normal-weight women pregnant with twins should gain between 37 and 54 pounds, according to research from a Michigan State University professor who helped shape the recently released national guidelines on gestational weight gain.
Purdue University researchers have created magnetically responsive gold nanostars that may offer a new approach to biomedical imaging.
African American men could be putting their health at risk by avoiding disease screening, in the belief that the results might threaten their masculinity. Because they prove their masculinity through their sexuality and sexual performance, seeking medical advice including HIV/AIDS testing goes against their notion of masculinity. Waverly Duck, a Post Doctoral Associate from the Department of Sociology at Yale University in the US, argues that current leading theories of gender and masculinity and health behavior models are not relevant enough to African American men and their distinctive notion of masculinity. His results1 are published online in Springer"s Journal of African American Studies.
A sixteen-month study of consensus-based diagnosis of patients with disorders of consciousness has shown that 41% of cases of minimally conscious state (MCS) were misdiagnosed as vegetative state (VS), a condition associated with a much lower chance of recovery. Researchers writing in the open access journal BMC Neurology have demonstrated that standardized neurobehavioral assessment is more sensitive than diagnoses determined by clinical consensus.
A portable "lab on a chip" that can identify target molecules in blood samples has been created by European researchers. It is being used to measure fertility hormones and detect the genes associated with certain types of cancer.
Researchers at the University of California, Berkeley, are
Cardica, Inc. (Nasdaq: CRDC) announced that the full results of the PAS-Port system multi-center pivotal trial, known as the EPIC trial, were published in the July issue of the peer-reviewed publication The Journal of Thoracic and Cardiovascular Surgery. The PAS-Port system, which received 510(k) clearance from the U.S. Food and Drug Administration (FDA) in September 2008, creates a secure connection, or anastomosis, between a vein graft and the aorta, the main artery in the human body, during coronary artery bypass grafting (CABG) procedures.
Two of the most recognized names in diabetes management - Medtronic, Inc. (NYSE: MDT) and Eli Lilly and Company (NYSE: LLY) - announced a strategic marketing collaboration to bolster each company"s commitment to help people with diabetes manage teir blood sugar using insulin therapy.
AnaSpec has introduced a wide selection of membrane potential fluorescent probes.
For years, George Forschler knew the mitral valve in his heart was failing and would eventually need repair or replacement. Concerned about the risks associated with open heart surgery the traditional way to access a mitral valve he did his best to postpone the inevitable. Forschler, a retired U.S. Air Force Brigadier General who now heads a consulting firm, kept his heart healthy by exercising at the gym and doing weekend chores on his farm near here.
The California Medical Association today praised the state Department of Insurance (DOI) for conducting a public hearing this week on its proposed regulations to prevent private insurers from unjustly canceling health coverage for patients after they get sick and file an expensive claim. The DOI released the proposed regulations last month.
Five centrist House Democrats, led by antiabortion-rights Rep. Tim Ryan (Ohio), on Tuesday issued a proposal that would neither require nor ban private insurers from covering abortion services as long as federal dollars are not used, the Washington Post"s "Capitol Briefing" reports. In a letter sent to House Speaker Nancy Pelosi (D-Calif.), Ryan and Reps. Dale Kildee (Mich.), James Langevin (R.I.), Artur Davis (Ala.) and Kendrick Meek (Fla.) said that their proposal "maintains the current status quo in the private market" and would not "preempt constitutionally permissible" state restrictions related to abortion, such as parental notification laws. The representatives called their proposal a "common ground solution." Current federal law prohibits the use of federal Medicaid funds for abortion services in nearly all circumstances. The lawmakers said that they are "increasingly concerned about potential roadblocks around the issue of abortion" in the health reform debate in Congress. According to "Capitol Briefing," antiabortion-rights Democrats are concerned that health reform legislation could lead to indirect federal funding of abortion services through private insurers participating in a proposed health insurance exchange (Eggen, "Capitol Briefing," Washington Post, 7/21). In the letter, the representatives said that they would like to include language in the final health reform bill "that makes clear that no insurance company will be required to pay for an abortion except in extraordinary circumstances." In addition, insurance providers would not be prohibited from paying for abortion services "so long as health insurance plans offered in the exchange that choose to provide abortion coverage pay for those services with funds that are separate and distinct from any federal subsidies," the letter said. Ryan said he hopes the proposal will be introduced in committee on Wednesday as an amendment (Smith, Politico, 7/21).House Members Step Up Efforts To Exclude Abortion CoverageMeanwhile, antiabortion-rights House members are intensifying their efforts to exclude abortion coverage from the chamber"s health reform bill (HR 3200), which they said includes a "hidden mandate" that would allow federal money to cover the procedure, the AP/Houston Chronicle reports. Rep. Bart Stupak (D-Mich.) said that he plans to join other antiabortion-rights House members at a news conference on Wednesday to criticize the legislation. Stupak helped draft a June 25 letter to Pelosi saying that he and 19 other Democrats would not support any health reform bill "unless it explicitly excludes abortion from the scope of any government-defined or subsidized health insurance plan." The bill does not mention abortion, which supporters say means that the legislation is neutral on the issue (Alonso-Zaldivar, AP/Houston Chronicle, 7/22).Antiabortion-Rights Coalition Launches CampaignA coalition of antiabortion-rights groups this week is launching a three-week campaign aimed at excluding abortion coverage from health reform legislation, Politico reports. The coalition includes James Dobson, founder of Focus on the Family; Tony Perkins, president of the Family Research Council; Richard Land of the Southern Baptist Convention; David Bereit of 40 Days for Life; and Charmaine Yoest, president of Americans United for Life. Yoest said AUL intends to send a letter to President Obama on Thursday citing its "belief that the bills are intended to include abortion."Laurie Rubiner, vice president for public policy and advocacy at the Planned Parenthood Federation of America, said that abortion is "not mandated any more than any other service or procedure in health reform." She added that excluding abortion coverage could result in women losing the coverage they currently have under private plans. The abortion-rights opponents" demand to exclude abortion coverage "violates the first principle of health care reform, which is: Don"t make people worse off under health care reform than they are today," Rubiner said (Smith, Politico, 7/22).
The Senate Judiciary Committee on Tuesday postponed its vote on Supreme Court nominee Sonia Sotomayor until July 28 at the request of Republican members who said they need one more week to review written answers she recently submitted to the panel, CongressDaily reports. Both Republicans and Democrats expect Sotomayor to be approved by the committee and confirmed by the Senate, CongressDaily reports (CongressDaily, 7/21).The delay came as Senate Republicans continued to weigh whether they would vote to confirm Sotomayor, the Wall Street Journal reports. Sen. Susan Collins (R-Maine) announced plans to vote for Sotomayor and issued a statement calling the judge "committed to applying the law impartially without bias or favoritism." Four other moderate Republicans have said they will support Sotomayor, and Senate Judiciary Committee Chair Patrick Leahy (D-Vt.) indicated that more might follow suit. "There are a number of Republicans who have announced they plan to vote for her," Leahy said, adding, "There are a number of others who"ve not made that announcement yet, but plan to vote for her" (Peterson, Wall Street Journal, 7/21). Leahy said he is confident that Sotomayor will be confirmed in time for the Supreme Court"s first meeting on Sept. 9.Some strong conservatives, including Senate Minority Leader Mitch McConnell (Ky.), have said they will oppose Sotomayor (Hirschfeld Davis, AP/Denver Post, 7/22). Among the Senate Republicans who have not announced their intentions are Sens. John Cornyn (Texas), who serves on the Judiciary Committee, and Judd Gregg (N.H.) (Wall Street Journal, 7/21).NARAL Endorses Sotomayor NARAL ProChoice America recently said that it will endorse Sotomayor, the AP/Seattle Times reports. The group said that Sotomayor"s testimony shows that she is a stronger supporter of privacy rights than the last two Supreme Court nominees -- Chief Justice John Roberts and Justice Samuel Alito. Sotomayor said several times during her confirmation hearings that privacy rights include a woman"s right to have an abortion, NARAL said. According to the AP/Times, NARAL did not endorse Sotomayor until now because of uncertainty over her views on abortion rights (Hirschfeld Davis, AP/Seattle Times, 7/21).
Insurers sometimes cherry-pick facts to make their case against certain aspects of reform efforts, including a public plan, The Washington Post reports.
"Americans are showing more confidence in their ability to get and afford the health care they need, according to a poll released Tuesday," The Associated Press reports on Cleveland.com. The story continues: "Whites, though, are likelier to feel that way than minorities. And large numbers of people are worried about whether they will have future health coverage, with nearly one in four concerned that family medical bills will drive them into bankruptcy."
American Indian teenagers become parents at twice the rate of other American teenagers. Many of these teens have greater environmental and behavioral challenges associated with living on reservations, including higher rates of poverty, increased rates of unemployment and school drop-out, higher rates of alcohol and drug abuse, impaired access to healthcare, as well as increased risk of domestic violence and suicide over the general population.
"A bitter Congressional fight over the cost of superexpensive biotechnology drugs has come down to a single, hotly debated number: How many years should makers of those drugs be exempt from generic competition?" The New York Times reports. "At issue are such drugs as Biogen Idec"s Avonex, for multiple sclerosis, which can cost more than $20,000 a year; Genentech"s Avastin for cancer, which can cost more than $50,000; and several Genzyme drugs for rare diseases that can cost $200,000 a year or more. ò€¦ Because they are hard to copy exactly, they have not been subject to the generic competition that eventually knocks down the price of drugs like Lipitor and Prozac."
The U.N. on Tuesday said "it is running a record funding-shortfall of $4.8 billion for its aid operations in 16 crisis-ridden countries" and has received "less than half of the $9.5 billion it needs to carry out it humanitarian operations this year," VOA News reports (Schlein, 7/21).
Chicago high school students interested in science and health care will get a chance to learn about diagnostic tests and the laboratory professionals who perform them during the American Association for Clinical Chemistry"s 2009 Clinical Lab Expo on July 21 and 22.
Today at the American Association for Clinical Chemistry"s Clinical Lab Expo in Chicago, Abbott (NYSE: ABT) announced the launch of a new diagnostic instrument - the ARCHITECT® c4000® clinical chemistry analyzer which performs diagnostic tests that monitor general health including a patient"s levels of sodium, potassium, chloride and organ function.
Employers will hire 22 percent fewer college graduates in 2009 than they did last year, according to the National Association of Colleges and Employers. That means thousands of Pennsylvania college students graduating this spring may be without health insurance coverage due to unemployment or time elapsing before starting a new job.
Dr. Donald Palmisano, former president of the American Medical Association and current spokesman for the Coalition to Protect Patients" Rights (Coalition) and over forty doctors from across the country today urged Members of Congress to slow down health system reform and do it right. The Coalition held a press conference at the National Press Club to urge legislators to put patients first when developing a system overhaul.
Scientists have linked an overactive response by one of the immune system"s key weapons against infection - natural killer, or NK, cells - to the onset of biliary atresia in infants, a disease where blocked bile ducts can cause severe liver damage and death.
Findings from the largest study to date comparing the efficacy of competing treatments for chronic hepatitis C infection (HCV) show that the regimens are similar when it comes to safety and their ability to provoke long-term viral eradication, according to researchers at Duke University Medical Center. Still, subgroup analysis reveals provocative data suggesting some approaches might be better than others for women and minorities.
Americans living with undiagnosed diabetes incur an estimated $18 billion in healthcare expenditures each year, or $2,864 per person in medical services and lost productivity from diabetes-related complications, according to a new study initiated by the National Changing Diabetes(R) Program and published in the journal, Population Health Management.
Mice with a defective mitochondrial protein called MCLK1 produce elevated amounts of reactive oxygen when young; that should spell disaster, yet according to a study in this week"s JBC these mice actually age at a slower rate and live longer than normal mice.
Stephania Cormier, PhD, Associate Professor of Pharmacology at LSU Health Sciences Center New Orleans, has shown for the first time that early exposure to environmentally persistent free radicals (present in airborne ultrafine particulate matter) affects long-term lung function. She recently presented her latest research data at the 11th International Congress on Combustion By-Products and Their Health Effects at the Environmental Protection Agency Conference Center in Research Triangle Park, N.C.
Topical Treatment Improves Wound Healing
Health Minister Edwina Hart is reminding people that Wales will not be part of the National Pandemic Flu Service (NPHS) when it goes live in England.
New research reveals Brits prefer to rearrange or cancel their summer holiday than go with a friend who has mental illness. The British would prefer to go on their summer holiday with a friend who has a criminal record than go with a friend who has a mental health problem, a new survey as part of the Time to Change campaign [1] has found.
Injured heart tissue normally can"t regrow, but researchers at Children"s Hospital Boston have now laid the groundwork for regenerating heart tissue after a heart attack, in patients with heart failure, or in children with congenital heart defects. In the July 24 issue of Cell, they show that a growth factor called neuregulin1 (NRG1), which is involved in the initial development of the heart and nervous system, can spur heart-muscle growth and recovery of cardiac function when injected systemically into animals after a heart attack.
Earlier this month the University of Wisconsin Cancer Center Riverview became the first medical facility in the world to treat patients with a breakthrough treatment of skin cancer. Located within Riverview Hospital, Wisconsin Rapids, the UW Cancer Center Riverview is the first to treat skin cancer patients with the FDA-cleared Axxent(R) Electronic Brachytherapy System from Xoft, Inc. Electronic Brachytherapy, eBx(TM) , delivers a high therapeutic dose to a cancer tumor while sparing nearby normal tissue by using a miniaturized X-ray rather than radioactive isotopes.
A research published ahead of print in the British Journal of Ophthalmology suggests certain types of drugs prescribed to lower blood pressure seem to increase the risk of corrective cataract surgery.
Ozone exposure, even at levels deemed safe by current clean air standards, can have a significant and negative effect on lung function, according to researchers at the University of California Davis.
The risk of developing deep vein thrombosis during a long flight is often overestimated. According to the German Institute for Quality and Efficiency in Health Care (IQWiG), this condition is very unlikely in healthy travellers. When people wear a cast or splint after a sports accident, on the other hand, many are not aware that they have an increased risk of deep vein thrombosis in their leg and pelvic area. This is emphasised in information published on IQWiG"s website Informed Health Online.
A host of Democrats and Republicans now count themselves among the rolls of those who question the long-term costs and repercussions of health reform as reform efforts slow considerably, The New York Times reports.
"A typhoid vaccine proved effective in the slums of India, where it not only helped prevent infection in children who received it, but also those in close contact who were unvaccinated," according to a New England Journal of Medicine study published on Thursday, the AP/Washington Post reports (Chang, 7/22).
Inter Press Service examines how "[f]ailure to sustain funding for HIV/AIDS treatment programmes could lead to a rising number of deaths, particularly in Africa." Examples cited by the news service include: "The Tanzanian government ò€¦ had to reduce its HIV budget by a quarter, while Swaziland lowered its 2011 treatment coverage target from 60 percent to 50 percent, which will affect about 40,000 HIV-positive people." In Uganda, "some PEPFAR-funded non-governmental organizations" were "instructed to stop enrolment in treatment," and "Malawi is expecting national drug shortages and in the process of putting into place an emergency plan."
A San Mateo County, Calif., program that provides in-home case management services for people living with HIV/AIDS, as well as other programs that assist people living with the virus, could be eliminated, forcing patients to obtain more expensive outpatient care, if proposed state budget cuts are approved, the San Francisco Examiner reports. John Conley, director of public health programs for San Mateo County, said case management services are alternatives to hospitalization or nursing facility care, which are more expensive. "Additionally, the state"s AIDS office will not allow municipalities to make reductions to case management activities or other requirements such as client/staff ratios, according to county officials," the Examiner reports. Conley said, the state is paying half the costs of the program, but the program is "becoming very, very expensive to run" (Koskey, 7/23).
Researchers "believe they have found a "missing link" in the evolution of the virus that causes AIDS," based on findings from a
Volunteers are needed for the final phase of a Diabetes UK-funded study investigating whether flavonoids - compounds found in chocolate - can protect older women with diabetes from heart disease.
A study conducted by the American Society of Clinical Oncology (ASCO) finds that different interpretations of the U.S. Health Insurance Portability and Accountability Act (HIPAA) Privacy Rule can result in significant delays or abandonment of important clinical cancer research projects. The study also outlines measures that research sites can undertake to resolve these differences and speed the pace of research. The study results were published online today by the Journal of Clinical Oncology in an ASCO special article, "The Impact of the Privacy Rule on Cancer Research: Variations in Attitudes and Application of Regulatory Standards".
The U.S. Department of Energy"s Brookhaven National Laboratory and Hybridyne Imaging Technologies, Inc., of Toronto, Canada, have won a 2009 R&D 100 Award for developing a compact gamma camera for high-resolution imaging of prostate cancer. The camera system, called ProxiScan, is a nuclear medical instrument that can localize cancer tissue in the prostate gland in detail at an early stage, which is important for the successful diagnosis and early treatment of the potentially deadly disease.
In her 1984 boot camp graduation photo, Adrienne Fitts is smiling. Her hair is neatly groomed, her Navy cap and dress whites are spotless and she is regulation fit and trim.
Promedior, Inc. announced the initiation of a Phase 1 clinical trial of PRM-151, a novel compound in development for the treatment of fibrotic diseases and tissue remodeling. The Phase 1 dose escalation study is designed to evaluate the safety, tolerability, pharmacokinetics and exploratory pharmacodynamics of ascending single intravenous doses of PRM-151 in healthy subjects. The study is being conducted at the Centre for Human Drug Research in The Netherlands.
Two new studies reveal a way to increase the body"s appetite for gobbling up the cancer stem cells responsible for acute myeloid leukemia (AML), a form of cancer with a particularly poor survival rate. The key is targeting a protein on the surface of those cells that sends a "don"t eat me" signal to the macrophage immune cells that serve as a first line of defense, according to the reports in the July 24th issue of the journal Cell, a Cell Press publication.
Five Yale School of Medicine investigators have received of new Pilot Project Program grants from Women"s Health Research at Yale. They will study a variety of women"s health areas and gender differences that affect disease and behavior.
Cyberonics, Inc. (Nasdaq: CYBX) announced that the U.S. Food and Drug Administration ("FDA") has approved the company"s proposal to amend the protocol of its D-21 post-approval dosing study in depression patients treated with VNS Therapy(TM).
Sanofi-aventis (EURONEXT: SAN and NYSE: SNY) and its wholly owned subsidiary, BiPar Sciences, announced the initiation of the pivotal Phase III trial for BSI-201 in combination with chemotherapy in patients with metastatic triple-negative breast cancer (mTNBC), defined by tumors lacking expression of estrogen, progesterone receptors and without over-expression of HER2. BSI-201 is a novel investigational targeted therapy which inhibits poly (ADP-ribose) polymerase (PARP1), an enzyme involved in DNA damage repair.
Sanofi Pasteur, the vaccines division of the sanofi-aventis Group (EURONEXT: SAN and NYSE: SNY), announced it has received an order from the French Ministry of Health to produce a vaccine against the novel A(H1N1) influenza virus.
Appendicitis is a condition in which the appendix becomes swollen, inflamed, filled with pus. The appendix is a small pouch shaped like a small finger. It is on the right side of the abdomen, connected to the colon.
Pleurisy, also known as pleuritis, is a condition that results from the swelling of the linings of the lungs and chest. The pleural cavity (area between lungs and inner chest wall) is created by two lubricated surfaces called pleura, the inner pleura lining the lungs and the outer lining the chest wall.
The following summarizes selected women"s health-related blog entries.~ "Democratic Bill Could Be a Preview of Obama"s Abortion Plan," Dan Gilgoff, U.S. News & World Report"s "God and Country": A recently introduced bill aimed at reducing the need for abortion is "big news because moderate to liberal faith-based advocates are urging the White House to adopt the bill ... as the core of its forthcoming "common ground" plan on abortion and reproductive health," Gilgoff writes. Some conservative religious groups, including the Southern Baptist Convention and the U.S. Conference of Catholic Bishops, "have warned the White House" that the bill is a "deal breaker" for them because of its support for comprehensive sex education and contraception, he writes. The White House "has refused to say which way it"s leaning," Gilgoff writes, adding the Obama administration could "buck" the groups that support the bill and "get behind" the Pregnant Women Support Act, "which is generally considered more robust on reducing demand for abortions and which leaves out contraceptive funding." However, he concludes, "that would be a pretty big surprise" (Gilgoff, "God and Country," U.S. News & World Report, 7/23).~ "New Report: Abortion Providers = American Human Rights Defenders, Now Under Increasing Attack," Jodi Jacobson, RH Reality Check: A new Center for Reproductive Rights report "calls on both the federal and state governments to address the growing threats against and stigmatization and abuse of abortion providers throughout the United States," Jacobson writes. The report "focuses on a key obstacle to the realization of women"s reproductive rights ... and recognizes their work as human rights defenders," she writes, adding that the U.S. has "historically been a leader both in creating and in encouraging accountability to human rights principles throughout the world." However, "[a]ccess to reproductive health care generally and abortion care specifically are basic human rights largely ignored within the context of U.S. domestic politics," Jacobson writes, noting that abortion access in the U.S. "has been increasingly limited due to the range of obstacles created through anti-choice advocacy." The report highlights several "types of rights violations [that] are most pervasive in limiting women"s choices and the rights of abortion providers," including "intimidation and harassment," "stigma" and "legal restrictions." The report makes a "series of recommendations for change at the state and local level for changes in policy and in law enforcement practices, as well as for the federal government, medical community and non-governmental organizations," Jacobson concludes, adding that the report "makes a special plea for the United Nations Special Rapporteur to document violations of women"s human rights in the United States" (Jacobson, RH Reality Check, 7/22).~ "Sixteen Governors Call on Congress To Include Medicaid Family Planning State Option in Health Reform," Jodi Jacobson, RH Reality Check: "Sixteen governors have written a letter to both Senate and House Leadership "expressing strong support for the Medicaid Family Planning State Option,"" which is included in President Obama"s fiscal year 2010 budget proposal, Jacobson writes. The governors wrote, "Many of our states have created family planning expansion programs, though we have done so with great difficulty," adding, "Since the early 1990s, 27 states have been granted federal waivers to expand their Medicaid family planning coverage. These demonstration projects have been unqualified successes, providing care to millions of women while saving states [millions] of dollars." Jacobson continues, "The current Medicaid waiver process, however, "puts unnecessary roadblocks in the way of our efforts to maintain and expand coverage for family planning services,"" according to the governors. She adds, "Passing this law as part of health care reform "would give us the needed flexibility to quickly and efficiently expand cove
President Obama rallied support for health care at a town hall meeting in Shaker Heights, Ohio, on Thursday, despite news of a legislative delay in the Senate.
Various news outlets examined the powerful roles members of the Obama administration are taking in the health care debate.
Insurers are testing a concept called "medical home" that uses electronic records and coordinates care, and could transform the delivery of health care. Advocates say such medical homes could save consumers time and money and insurers back the idea. Meanwhile, skeptics say financial savings still need to be proven and incentives need to put into the system to encourage such care.
New regulations seek to crack down on a little known form of identity theft -- medical identity theft, according to Kaiser Health News. "Armed with as little as a stolen name, Social Security number and date of birth, an imposter can walk into a doctor"s office or hospital and receive services billed to the victim or the insurance provider. Although few statistics are available, the Federal Trade Commission reports that medical identity theft accounts for 1.3 percent to 3 percent of all identity theft crime -- about 250,000 cases each year."
"Global health officials are scrambling to try to prevent the spread of the H1N1 swine flu virus, with U.S. officials moving Thursday with a recommendation that the Food and Drug Administration (FDA) approve or license a [new H1N1] vaccine," without waiting on the results from "clinical trials to test its safety and efficacy," Wall Street Journal reports (Dooren/Winning, 7/24). Reuters reports that FDA officials vowed during a meeting Thursday to closely monitor for any harmful side effects from the vaccine (Fox, 7/23).
"Despite making strides in addressing HIV/AIDS, we have not reached all individuals and communities with the full range of prevention tools needed to reverse the epidemic," Jirair Ratevosian, chair of the American Public Health Association International Health Section"s Advocacy and Policy Committee, writes in a Washington Post letter to the editor. Ratevosian continues, "Congress has a chance to help by lifting the ban on federal funding for syringe exchange programs," adding, "Such programs do more than just distribute clean syringes; they link people into the health care system and drug treatment programs." Ratevosian also discussed support of needle exchange programs by several national health organizations and concludes, "It is imperative that effective approaches to preventing HIV be accessible without delay" (Ratevosian, 7/24).
New research shows that training your brain may be just as effective as training your muscles in preventing ACL knee injuries, and suggests a shift from performance-based to prevention-based athletic training programs.
AARP Executive Vice President John Rother issued the following statement in response to recent commentary by Betsy McCaughey in various media outlets on health care reform measures passed or currently being considered by Congress.
Tranzyme Pharma announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation for the Company"s oral gastrointestinal (GI) prokinetic drug candidate TZP-102, for the treatment of gastroparesis in diabetic patients. According to the FDA, gastroparesis is a serious complication of diabetes mellitus that affects approximately 30-60% of diabetic patients.
The Royal Pharmaceutical Society of Great Britain has published its fourth Pharmacy
Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE), announced the publication in Fertility and Sterility of data from a Phase 3 clinical study that showed that the investigational compound bazedoxifene/conjugated estrogens (BZA/CE) significantly reduced the frequency and severity of hot flushes and improved measures of vaginal atrophy when compared to placebo. In this study, uterine bleeding was not statistically different from placebo and the rate of endometrial hyperplasia in doses being considered for therapeutic use was Fertility and Sterility, is from the Selective estrogens Menopause And Response to Therapy (SMART-1) clinical trial. SMART-1 was designed to explore the hypothesis that bazedoxifene, when paired with conjugated estrogens, may have the potential to eliminate the need for progestin in menopausal therapy in women with an intact uterus. BZA/CE is characterized by Wyeth as a TSEC (tissue selective estrogen complex) as it combines a selective estrogen receptor modulator (SERM) with conjugated estrogens.
A patient centered medical home pilot project that could become a model for South Carolina has completed its first quarter with 1,110 patients enrolled. It is also attracting the attention of S.C. physicians not involved in the program, and S.C. businesses are interested in it as a means to managing their health care costs.
Eli Lilly and Company (NYSE: LLY) and BioMS Medical Corp. (TSX: MS) announced that dirucotide did not meet the primary endpoint of delaying disease progression, as measured by the Expanded Disability Status Scale (EDSS), during the two-year MAESTRO-01 Phase III trial in patients with secondary progressive multiple sclerosis (SPMS). In addition, there were no statistically significant differences between dirucotide and placebo on the secondary endpoints of the study.
Relistor (Methylnaltrexone) is a medication for patients who suffer from constipation caused by opioid drugs. Opioid drugs are used for pain relief. An opioid is a chemical that binds to opioid receptors that exist mainly in the central nervous system and the gut (gastrointestinal tract). When people take opioids they have a lower perception of pain, a lower reaction to pain, as well as a higher pain tolerance - in other words, opioids provide effective pain relief. However, opioids also cause constipation.
The House on Friday voted 264-153 to approve its fiscal year 2010 Labor-HHS-Education spending bill (HB 3293) after voting on five amendments addressing price and policy issues, CQ Today reports. The bill would appropriate $730.5 billion. The Senate Appropriations Committee is scheduled to begin markup of its version of the bill on July 28.The House voted 183-247 to reject an amendment offered by Rep. Mike Pence (R-Ind.) that would have prohibited family planning funding through the Title X program to Planned Parenthood clinics. The House also voted 211-218 to reject an amendment by Rep. Mark Souder (R-Ind.) that would have stripped language to lift the ban on federal funding for needle-exchange programs. Lawmakers did approve an amendment offered by Rep. Darrell Issa (R-Calif.) to strip $5 million in funding for three NIH grants to study the HIV/AIDS risks associated with alcohol and substance use among sex workers in Asia and alcoholics in Russia (Wolfe, CQ Today, 7/24).
The Health-Care Sacrifice The Washington Post
UNICEF Using SMS Text Messages To Fight Polio In Zambia
The Healthcare Association of New York State (HANYS) announced that Dennis P. Whalen, Director of State Operations in the Governor"s office, will join the Association on September 9 as Executive Vice President. Mr. Whalen will play a key role in shaping HANYS" overall policies and in helping prepare the membership for national health care reform.
Since trade liberalization between Central and North America, imports and availability of processed, high-fat and high-sugar foods have increased dramatically. Researchers writing in BioMed Central"s open access journal Globalization and Health link this influx of American junk food to a "nutrition transition" in Central American countries, with a growing burden diet-related chronic disease.
A lack of sunlight is associated with reduced cognitive function among depressed people. Researchers writing in BioMed Central"s open access journal Environmental Health used weather data from NASA satellites to measure sunlight exposure across the United States and linked this information to the prevalence of cognitive impairment in depressed people.
The Senate Health, Education, Labor and Pensions Committee on Tuesday began marking up a bill (S 982) that would allow FDA to regulate tobacco products, CongressDaily reports. The bill would allow FDA to place larger, color warning labels about the health risks of smoking on cigarette packs, as well as to regulate the marketing of tobacco products and advertising to children. The agency could not ban tobacco products or eliminate nicotine from cigarettes, but it could regulate their production and ban flavored cigarettes other than menthol. Sen. Chris Dodd (D-Conn.) said, "Over the years, this bill has been reviewed; it has been vetted; it has been debated, over and over and over again. The time has come to act." The House in April passed its version of the bill, 298-112 (Hunt, CongressDaily, 5/20). The committee by voice vote approved an amendment proposed by Sen. Jeff Merkley (D-Ore.) that would give FDA priority to review products that contain nicotine, such as candies. Committee ranking member Mike Enzi (R-Wyo.) proposed two amendments, one that would have given regulatory authority over tobacco to CDC and another that would have ordered FDA to study which flavors to ban, instead of a current provision that bans specific flavors. Both amendments were defeated. Enzi said, "I think the FDA is the wrong regulator. It approves cures, not poisons." The only Democrat who opposed the bill was Sen. Kay Hagan (N.C.), who said the measure would harm the tobacco industry in her home state (Armstrong, CQ HealthBeat, 5/19). The panel"s other member from North Carolina, Sen. Richard Burr (R), said he would filibuster the bill. He said, "I put my fellow senators on notice: This is something that will be a much longer time on the floor than it will be in this hearing" (CongressDaily, 5/20). The committee plans to continue marking up the bill Wednesday and possibly Thursday.The Obama administration has expressed its support for the bill (CQ HealthBeat, 5/19). FDA Commissioner Margaret Hamburg also has said her agency should regulate tobacco (Armstrong, CQ HealthBeat, 5/18).
Long-term survivors of cancer that developed in adulthood are at increased risk of experiencing serious psychological distress, according to a report in the July 27 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Distinctive patterns of genes turned off - or left on - in healthy versus cancerous cells could enable early screening for many common cancers and maybe help avoid them, Medical College of Georgia scientists say.
Although macrophages are known as essential players in wound healing,
We"ve all experienced it after long hours driving, the eyelids getting heavy, a deep yawn, neck muscles relaxing, the urge to sleep, the head nodding down... But, you"re hands are still on the wheel and you only just stopped yourself nodding off in time to avoid the oncoming traffic.
It is widely known that the brain perceives information before it reaches a person"s awareness. But until now, there was little way to determine what specific mental tasks were taking place prior to the point of conscious awareness.
The cause of lung cancer in never-smokers is poorly understood, but a study led by investigators at the Ohio State University Comprehensive Cancer Center and at the National Cancer Institute has identified a molecule believed to play an early and important role in its development.
The Lymphoma Research Foundation (LRF) is pleased to announce that the 2009 Millennium Pharmaceuticals, Inc./Lymphoma Research Foundation Clinical Investigator Career Development Award has been awarded to Kai Fu, MD, PhD, Associate Professor at the Nebraska Medical Center in Omaha, Nebraska.
New research from the US suggests that divorce and widowhood damage health in ways that even getting married again doesn"t heal.
A new proposal from the Centers for Medicare and Medicaid Services (CMS) to cut payments for radiation therapy treatments would cause many cancer centers to close, stop accepting Medicare patients, lay off support staff and reduce services to cancer patients, according to a survey conducted by ASTRO, the American Society for Radiation Oncology.
Doctors are being reminded that assisting a suicide is illegal in England and Wales and that they should not give advice to patients to help them travel abroad to take their own lives.
The eyes of nocturnal bats possess two spectral cone photoreceptor types
÷£25 million announced to more than treble the number of NHS apprenticeships
Cardium Therapeutics (NYSE Amex: CXM) and its subsidiary Tissue Repair Company (TRC) provided an update on the completion of their MATRIX Phase 2b clinical study and announced plans to provide detailed safety and efficacy data for their Excellarate(TM) product candidate around the end of September. The MATRIX trial, a prospective, randomized, double-blind, placebo-controlled study, has enrolled 124 diabetic patients with non-healing, lower extremity neuropathic ulcers.