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Pitt Study Redefines Binge Drinking For Children And Adolescents
The criteria used to assess blood alcohol concentrations (BACs) and binge drinking behaviors in children and adolescents should be based on pediatric rather than adult physiology, according to a new University of Pittsburgh study in the June issue of Pediatrics.
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Deep Brain Stimulation Shows Promising Results For Some Patients With Cerebral Palsy
Deep brain stimulation improves movement skills and quality of life in some patients with a subtype of cerebral palsy (CP) (dystonia-choreoathetosis CP)*, and could be an effective treatment option for these patients, finds an Article published Online first and in the July edition of The Lancet Neurology.
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Rexin-G Controls Tumor Growth And Improves Survival In Chemotherapy-Resistant Sarcoma And Osteosarcoma: Phase I/II And Phase II Studies, ASCO 2009
Epeius Biotechnologies announced the results of two related studies using Rexin-G, a tumor-targeted anti-cancer agent designed to seek-out and destroy metastatic cancers that have spread throughout the body. While Rexin-G is currently approved for the treatment of all solid tumors in the Republic of the Philippines, Epeius Biotech is conducting a series of advanced Phase I/II studies and a Phase II confirmatory trial in the U.S. The Phase I/II study evaluating the safety and efficacy of Rexin-G in chemotherapy-resistant metastatic bone and soft tissue sarcomas (ASCO Annual Meeting 2009, #10513) demonstrated that Rexin-G was well-tolerated with no dose-limiting toxicity. Moreover, Rexin-G exhibited dose-dependent efficacy in terms of tumor control rates, progression-free survival, and overall survival, thus validating both the efficiency of the tumor-targeting technology and the pharmacological mechanisms of action.
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Task Deconstruction Facilitates Acquisition Of Transurethral Resection Of Prostate Skills On A Virtual Reality Trainer

UroToday.com - Increasingly surgical education is being focused on specific procedural training techniques. These researchers at the University of Minnesota have shown the importance of breaking the procedure down into its specific steps and deconstructing the various tasks applied to each step of the procedure. In a prospective randomized study with 18 trainees, who had no previous exposure to transurethral resection of prostate (TURP), half of the group was randomized to training using a full task TURP training format versus the other half undergoing task deconstruction training. Length of training time and the actual components of the procedural training were the same except for the steps and tasks were broken into distinct tasks in the study group. They discovered that trainees who underwent the deconstruction training showed significantly better improvement in their pre-test and post-test performance evaluation with regard to the amount of tissue resected and grams resected over the total time of using the cutting pedal. There was no significant difference noted in the number of bleeders coagulated, fluid consumed compared to grams of tissue resected or bleeders coagulated compared to time on the coagulation pedal. There was also no difference in the perforation rate between the two groups. However, interestingly the group of trainees who underwent the curriculum with task deconstruction had a higher approval rating of the simulator training compared to the group who underwent the full task training technique. While it may seem intuitive that task deconstruction is superior to full task training, in novice surgeons the confirmation of this educational technique is important as the surgical disciplines begin to develop virtual reality simulated based surgical training. Attention to curriculum development and the stepwise learning of the surgical procedure are critical elements of surgical education. Kishore TA, Beddingfield R, Holden T, Shen Y, Reihsen T, Sweet RM J Endourol. 2009 Apr;23(4):665-8. doi:10.1089/end.2008.0531 Written by UroToday.com Contributing Editor Elspeth M. McDougall, MD, FRCSC, MHPE UroToday - the only urology website with original content written by global urology key opinion leaders actively engaged in clinical practice. To access the latest urology news releases from UroToday, go to: www.urotoday.com Copyright © 2009 - UroToday


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