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New One-Year Data From REMICADE(R) SONIC Trial Show Sustained Efficacy Compared With Azathioprine In Treatment Of Crohn's Disease
New long-term findings from the Phase 3b study of patients with moderately to severely active Crohn"s disease having inadequate response to conventional therapies, but naive to immunomodulators and biologic therapy, were presented at Digestive Disease Week today. Data from the SONIC study showed that a greater proportion of patients receiving REMICADE (infliximab) maintained steroid-free remission at one year, compared with patients receiving azathioprine alone.
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Doctors And Software Engineers Pioneer An Advanced Sepsis Detection And Management System
When Jason Martin gives a talk about his research, he begins with the dramatic story of Mariana Bridi da Costa: The young Brazilian supermodel died from severe sepsis in January after amputation of both her hands and feet failed to stop its spread.
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Insights Into Failed HIV-1 Vaccine Trial: Study
Following the disbandment of the STEP trial to test the efficacy of the Merck HIV-1 vaccine candidate in 2007, the leading explanation for why the vaccine was ineffective - and may have even increased susceptibility to acquiring the virus - centered on the hypothesis that high levels of baseline Ad5-specific neutralizing antibodies may have increased HIV-1 acquisition among the study subjects who received the vaccine by increasing Ad5-specific CD4+ T-cells that were susceptible to HIV-1 infection.
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Sensory Impairment Among Older U.S. Workers Raises Risk Of Injury

A new study analyzing the prevalence of sensory impairment among older U.S. workers found that hearing impairment prevalence was three times that of visual impairment, and that 38 percent of older workers reported experiencing either impairment. Using 1997-2004 national survey data, researchers evaluated the prevalence of sensory impairment among U.S. workers age 65 years and older. Farm operators, mechanics and motor vehicle operators had the highest prevalence of sensory impairment. The study"s authors conclude, "Our findings suggest a need for preventative measures among potentially vulnerable worker groups with sensory impairment. Research is needed to determine whether sensory aids and other workplace accommodations enhance worker productivity and job satisfaction as well as reduce injury risk." American Journal of Public Health


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