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Revealing Leukemia-Initiating Cells
Two new studies reveal a way to increase the body"s appetite for gobbling up the cancer stem cells responsible for acute myeloid leukemia (AML), a form of cancer with a particularly poor survival rate. The key is targeting a protein on the surface of those cells that sends a "don"t eat me" signal to the macrophage immune cells that serve as a first line of defense, according to the reports in the July 24th issue of the journal Cell, a Cell Press publication.
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ASCO Study Finds Varying Interpretation Of HIPAA Privacy Rule Can Delay Cancer Research
A study conducted by the American Society of Clinical Oncology (ASCO) finds that different interpretations of the U.S. Health Insurance Portability and Accountability Act (HIPAA) Privacy Rule can result in significant delays or abandonment of important clinical cancer research projects. The study also outlines measures that research sites can undertake to resolve these differences and speed the pace of research. The study results were published online today by the Journal of Clinical Oncology in an ASCO special article, "The Impact of the Privacy Rule on Cancer Research: Variations in Attitudes and Application of Regulatory Standards".
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The PATH Malaria Vaccine Initiative And Crucell Announce Collaboration To Test New Adenovirus-based Malaria Vaccine Approach
The US-based PATH Malaria Vaccine Initiative (MVI), the United States Agency for International Development (USAID) Malaria Vaccine Development Program (MVDP), and Dutch biopharmaceutical company Crucell N.V. (Euronext, Nasdaq: CRXL; Swiss Exchange: CRX) today announced a collaboration to accelerate development of a promising type of malaria vaccine. Through funding from the USAID MVDP, the partners will conduct studies to determine the effectiveness of Crucell"s novel prime-boost vaccine approach against the malaria parasite, Plasmodium falciparum. This approach uses Crucell"s proprietary recombinant adenoviruses (a type of virus associated with the common cold and other mild respiratory infections) to deliver a malaria antigen to the immune system.
Nutrition

It Is Better To Be In The Hospital For Treating Bulimia Nervosa?

A German study published in the current issue of Psychotherapy and Psychosomatics addresses the differences between inpatient versus day clinic treatment of bulimia nervosa. In bulimia nervosa, more intense treatments are recommended if outpatient treatment fails. This is the first randomized controlled trial comparing the options of inpatient versus day clinic treatment. Patients with severe bulimia nervosa were randomly assigned to inpatient or day clinic treatment of similar length and intensity. Specific and general psychopathology was assessed at the end of treatment and a 3-month follow-up. Fifty-five patients were randomized; 22 day clinic patients and 21 inpatients started the program. At the end of treatment, a significant reduction of general and specific pathology was found in both settings. Following discharge, there was more deterioration in bulimic symptoms after inpatient treatment, but overall, results were comparable. Inpatient and day clinic programs are effective treatments for severely disturbed bulimic patients with similar results at the 3-month follow-up. Further follow-up will show if a higher instability of results after inpatient treatment is of importance in the long term. Psychotherapy and Psychosomatics


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