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FDA Fast Track Status For Oral GI Prokinetic Drug Candidate TZP-102 - For Gastroparesis In Diabetic Patients
Tranzyme Pharma announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation for the Company"s oral gastrointestinal (GI) prokinetic drug candidate TZP-102, for the treatment of gastroparesis in diabetic patients. According to the FDA, gastroparesis is a serious complication of diabetes mellitus that affects approximately 30-60% of diabetic patients.
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Increase Global Productivity By Giving Eyeglasses To All In Need
Huge economic gains could be made if eyeglasses were provided to approximately 150 million people in need, according to research published today in the international public health journal, the Bulletin of the World Health Organization.
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Black Men's Notion Of Masculinity Leads To Avoidance Of Health-Related Behaviors
African American men could be putting their health at risk by avoiding disease screening, in the belief that the results might threaten their masculinity. Because they prove their masculinity through their sexuality and sexual performance, seeking medical advice including HIV/AIDS testing goes against their notion of masculinity. Waverly Duck, a Post Doctoral Associate from the Department of Sociology at Yale University in the US, argues that current leading theories of gender and masculinity and health behavior models are not relevant enough to African American men and their distinctive notion of masculinity. His results1 are published online in Springer"s Journal of African American Studies.
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Emergency Physicians Don't Follow Established Clinical Guidelines For Diagnosing Patients With Possible Pulmonary Emboli

The number of MDCT examinations for suspected pulmonary emboli (PE) is rapidly increasing amongst ER patients, with a decrease in the number of positive studies. This may be due to a failure to adhere to established clinical guidelines for evaluating patients with suspected PE, according to a study performed at the Warren Alpert Medical School of Brown University and Rhode Island Hospital, Providence, RI. Current accepted clinical practice indicates that patients with a low clinical suspicion for PE should undergo D-dimer testing, then MDCT if positive. A total of 5,344 patients were reviewed. "42% of patients had a positive D-dimer exam and did not have a CT scan. Current protocols suggest that those patients should have had a scan," said Michael T. Corwin, MD, lead author of the study. "MDCT was performed in 7% of patients with negative D-dimer results, and the same protocols suggest that those patients should not have undergone a scan," said Dr. Corwin "Anytime a patient gets a CT scan there is a radiation dose. The evaluation of patients with suspected PE should include D-dimer and CT testing in a more standardized fashion so that we can save patients from having unnecessary CT scans. The D-dimer should only be used in patients with a relatively low suspicion of having PE. If the D-dimer test is positive, then patients should have the CT. If the test is negative then no scanning is needed," he said. "PE is very difficult to diagnose and there are a lot of factors you have to take into account. Most physicians are aware of D-dimer testing but whether or not they use it is often determined in a non-standardized fashion," he said. "MDCT is a great test. It"s fast, easy, accurate and provides physicians with tons of information. However we are ordering a lot of CT scans and what we"re finding is that a lot of these tests are negative. D-dimer testing does not rule out PE completely, but in patients with a low-probability of having it, based upon their presenting clinical picture, a negative D-dimer can spare them the radiation dose associated with MDCT," said Dr. Corwin. This study appears in the May issue of the American Journal of Roentgenology. About ARRS The American Roentgen Ray Society (ARRS) was founded in 1900 and is the oldest radiology society in the United States. Its monthly journal, the American Journal of Roentgenology, began publication in 1906. Radiologists from all over the world attend the ARRS annual meeting to participate in instructional courses, scientific paper presentations and scientific and commercial exhibits related to the field of radiology. The Society is named after the first Nobel Laureate in Physics, Wilhelm Rç¶entgen, who discovered the x-ray in 1895. American Roentgen Ray Society (ARRS)


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