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Provectus Reports Encouraging Clinical Data At ASCO On Treatment Of Metastatic Melanoma With PV-10
Provectus Pharmaceuticals, Inc. (OTC Bulletin Board: PVCT), a development-stage oncology and dermatology biopharmaceutical company, has announced interim data from the first 40 subjects in its Phase 2 clinical trial for the treatment of metastatic melanoma. PV-10 treatment was well tolerated and caused selective tumor destruction in the majority of subjects. Additional data on untreated tumors corroborated observations of a possible bystander effect seen during earlier Phase 1 testing. These data were presented today at the American Society of Clinical Oncology 2009 Annual Meeting, Abstract #9060, entitled "Chemoablation of melanoma with intralesional rose bengal (PV-10)," in the General Poster Session.
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National Organization for Women Establishes Kansas Abortion-Rights PAC To Fill Void After Death Of Abortion Provider Tiller
The Kansas chapter of the National Organization for Women has formed its own political action committee to replace ProKanDo, a PAC founded in 2002 by abortion provider George Tiller that was closed after his murder in May, the AP/Hays Daily News reports. ProKanDo spent more than $1 million over the last four years to advocate for abortion rights, assist candidates who support abortion rights and oppose antiabortion-rights candidates. The organization had more than 6,400 contributors but received between one-third and one-half of its annual funding from Tiller, according to former Director Julie Burkhart.NOW has scheduled a conference in Wichita on July 25 to discuss legislative strategy and Kansas elections. Marla Patrick, coordinator of NOW"s Kansas chapter,÷ said that although the new PAC will not have the same financial support from Tiller that ProKanDo received, his death has invigorated grassroots support. She added, "I think that can be every bit as effective, if not more so, especially in light of all the recent events" (Hegeman, AP/Hays Daily News, 7/18).
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Lower Cancer Risk For Obese Women Who Underwent Weight-Loss Surgery
An article published Online First and in the July edition of The Lancet Oncology indicates that weight-loss surgery known as bariatric surgery could be linked to a reduction in cancer risk in obese women, but not in obese men.
Mental Health

Discarded Fallopian Tubes Could Be Rich Of Stem Cells, Study

Fallopian tubes normally discarded after hysterectomies and other procedures could become rich potential s for mesenchymal stem cells which like other types of stem cell can be coaxed to develop into a variety of cell types, according to a new study by researchers in Brazil. Researchers from the University of Sç£o Paulo"s Human Genome Research Centre, which is directed by Dr Mayana Zatz conducted the study in collaboration with medical doctors from the University"s reproductive surgery department. The results are published as an online paper in BioMed Central"s open access Journal of Translational Medicine. The authors wrote that scientists have already discovered that umbilical cords, dental pulp and fat tissue, which they described as "biological discards", yield mesenchymal stem cells that can develop into muscle, fat, bone and cartilage tissue. This prompted them and other teams to look for more s, since stem cells obtained this way don"t raise the ethical problems that occur when stem cells are taken from embryos. As first author Tatiana Jazedje noted in a separate statement: "Use of human tissue fragments that are usually discarded in surgical procedures does not pose ethical problems." In this study the Brazilian team used fallopian tubes obtained from hysterectomy and other gynecological procedures undergone by fertile women aged from 35 to 55 who had been clear of any hormone treatments for at least three months beforehand. After isolating mesenchymal stem cells from the fallopian tubes, the researchers found that they were quite easy to expand in vitro where they differentiated readily into muscle, fat, cartilage and bone cell lines. The researchers found no abnormality in the chromosomes of the new cell lines, suggesting they had good chromosomal stability. They concluded that: "Human tube MSCs [mesenchymal stem cells] can be easily isolated, expanded in vitro, present a mesenchymal profile and are able to differentiate into muscle, fat, cartilage and bone in vitro. " Jazedje said that as well suggesting a possible new of stem cells for regenerative treatments, their findings will hopefully help reproductive science as a whole. "Human fallopian tube: a new of multipotent adult mesenchymal stem cells discarded in surgical procedures." Tatiana Jazedje, Paulo M Perin, Carlos E Czeresnia, Mariangela Maluf, Silvio Halpern, Mariane Secco, Daniela F Bueno, Natassia M Vieira, Eder Zucconi, Mayana Zatz. Journal of Translational Medicine 2009, 7:46. Published online 18 June 2009. doi:10.1186/1479-5876-7-46 BioMed Central. Written by: Catharine Paddock, PhD Copyright: Medical News Today Not to be reproduced without permission of Medical News Today


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